NP_001317545.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,268 Da
NCBI Official Full Name
adenylate kinase 4, mitochondrial isoform b
NCBI Official Synonym Full Names
adenylate kinase 4
NCBI Protein Information
adenylate kinase 4, mitochondrial
UniProt Protein Name
Adenylate kinase 4, mitochondrial
UniProt Synonym Protein Names
Adenylate kinase 3-like
UniProt Synonym Gene Names
NCBI Summary for AK4
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]
UniProt Comments for AK4
AK3L1: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP. Belongs to the adenylate kinase family.
Protein type: EC 2.7.4.10; EC 2.7.4.6; Kinase, other; Mitochondrial; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component: extracellular exosome; mitochondrial matrix; mitochondrion
Molecular Function: adenylate kinase activity; ATP binding; GTP binding; nucleoside diphosphate kinase activity; nucleoside phosphate kinase activity; nucleoside triphosphate adenylate kinase activity
Biological Process: AMP metabolic process; ATP metabolic process; brain development; GTP metabolic process; liver development; nucleobase, nucleoside and nucleotide interconversion; nucleoside diphosphate phosphorylation; nucleoside monophosphate phosphorylation; nucleoside triphosphate biosynthetic process; response to drug
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Products associated with AK4 elisa kit
Pathways associated with AK4 elisa kit
Diseases associated with AK4 elisa kit
Organs/Tissues associated with AK4 elisa kit
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