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b1AR elisa kit :: Bovine Anti beta 1 Adrenergic Receptor antibodies ELISA Kit

Scan QR to view Datasheet Catalog #    MBS747543 b1AR elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Anti beta 1 Adrenergic Receptor antibodies (b1AR), ELISA Kit

 Also Known As   

Bovine Anti beta 1 Adrenergic Receptor antibodies ELISA Kit

 Product Gene Name   

b1AR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 607276
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of b1AR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for b1AR purchase    MBS747543 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Anti beta 1 Adrenergic Receptor antibodies (b1AR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing b1AR. The ELISA analytical biochemical technique of the MBS747543 kit is based on b1AR antibody-b1AR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect b1AR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, b1AR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for b1AR elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for b1AR. It may not necessarily be applicable to this product.
 NCBI GI #    4557265
 NCBI GeneID    153
 NCBI Accession #    NP_000675.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000684.2 [Other Products]
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 UniProt Secondary Accession #    Q5T5Y4; Q9UKG7; Q9UKG8; B0LPE2 [Other Products]
 UniProt Related Accession #    P08588 [Other Products]
 Molecular Weight    51,323 Da
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 NCBI Official Full Name    beta-1 adrenergic receptor
 NCBI Official Synonym Full Names    adrenoceptor beta 1
 NCBI Official Symbol    ADRB1 [Similar Products]
 NCBI Official Synonym Symbols   
RHR; B1AR; ADRB1R; BETA1AR
[Similar Products]
 NCBI Protein Information    beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; adrenergic, beta-1-, receptor
 UniProt Protein Name    Beta-1 adrenergic receptor
 UniProt Synonym Protein Names   
Beta-1 adrenoreceptor; Beta-1 adrenoceptor
 UniProt Gene Name    ADRB1 [Similar Products]
 UniProt Synonym Gene Names    ADRB1R; B1AR; Beta-1 adrenoceptor [Similar Products]
 UniProt Entry Name    ADRB1_HUMAN
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 NCBI Summary for b1AR    The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]
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 UniProt Comments for b1AR    ADRB1: a GPCR-coupled 7 transmembrane receptor that binds epinephrine and norepinephrine with approximately equal affinity. Mediates the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Interacts with PIST and PSD-95. Localized at the plasma membrane and in the Golgi upon PIST overexpression. Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10q25.3

Cellular Component: integral to plasma membrane; early endosome; plasma membrane; nucleus

Molecular Function: protein binding; protein heterodimerization activity; receptor signaling protein activity; dopamine binding; drug binding; norepinephrine binding; epinephrine binding; alpha-2A adrenergic receptor binding; beta-adrenergic receptor activity; Ras guanyl-nucleotide exchange factor activity; beta1-adrenergic receptor activity; PDZ domain binding

Biological Process: fear response; diet induced thermogenesis; wound healing; apoptosis; positive regulation of apoptosis; lipid homeostasis; positive regulation of systemic arterial blood pressure; sensory perception of pain; positive regulation of saliva secretion; Rho protein signal transduction; regulation of inhibitory postsynaptic membrane potential; negative regulation of smooth muscle contraction; positive regulation of cAMP biosynthetic process; aging; glycogen catabolic process; negative regulation of multicellular organism growth; adenylate cyclase activation; regulation of calcium ion transport; memory; positive regulation of the force of heart contraction by norepinephrine; protein localization in organelle; heat generation; brown fat cell differentiation; response to cold; positive regulation of heart rate by epinephrine-norepinephrine; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure

Disease: Resting Heart Rate, Variation In
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 Research Articles on b1AR    1. beta1 and beta3-adrenergic receptors were expressed in retinal endothelial cells while beta2-adrenergic receptor was not detectable both at protein and mRNA levels.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with b1AR elisa kitPathways associated with b1AR elisa kit
 Reference Product  PubMed Publications
 ADRB2 elisa kit  >3138 publications with b1AR and ADRB2
 POMC elisa kit  >22 publications with b1AR and POMC
 GNAS elisa kit  >6 publications with b1AR and GNAS
 GHRH elisa kit  >1 publications with b1AR and GHRH
 ARRB2 elisa kit  >1 publications with b1AR and ARRB2
 ARRB1 elisa kit  >1 publications with b1AR and ARRB1
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenoceptors Pathway antibodies  Adrenoceptors Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
Diseases associated with b1AR elisa kitOrgans/Tissues associated with b1AR elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1196 publications with b1AR and Cardiovascular Diseases
 Heart Diseases Antibodies  >1014 publications with b1AR and Heart Diseases
 Heart Failure Antibodies  >602 publications with b1AR and Heart Failure
 Hypertension Antibodies  >339 publications with b1AR and Hypertension
 Cardiomegaly Antibodies  >263 publications with b1AR and Cardiomegaly
 Cardiomyopathies Antibodies  >247 publications with b1AR and Cardiomyopathies
 Myocardial Ischemia Antibodies  >228 publications with b1AR and Myocardial Ischemia
 Cardiomyopathy, Dilated Antibodies  >216 publications with b1AR and Cardiomyopathy, Dilated
 Arrhythmias, Cardiac Antibodies  >198 publications with b1AR and Arrhythmias, Cardiac
 Tachycardia Antibodies  >165 publications with b1AR and Tachycardia
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >2267 publications with b1AR and Heart
 Blood Antibodies  >1328 publications with b1AR and Blood
 Brain Antibodies  >628 publications with b1AR and Brain
 Kidney Antibodies  >183 publications with b1AR and Kidney
 Eye Antibodies  >79 publications with b1AR and Eye
 Embryonic Tissue Antibodies  >50 publications with b1AR and Embryonic Tissue
 Pineal Gland Antibodies  >38 publications with b1AR and Pineal Gland
 Bone Antibodies  >35 publications with b1AR and Bone
 Placenta Antibodies  >20 publications with b1AR and Placenta
 Testis Antibodies  >11 publications with b1AR and Testis
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