NP_942595.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,812 Da
NCBI Official Full Name
BMP-2-inducible protein kinase isoform a
NCBI Official Synonym Full Names
BMP2 inducible kinase
NCBI Protein Information
BMP-2-inducible protein kinase
UniProt Protein Name
BMP-2-inducible protein kinase
UniProt Synonym Gene Names
UniProt Entry Name
BMP2K_HUMAN
NCBI Summary for BMP2K
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for BMP2K
BIKE: May be involved in osteoblast differentiation. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; Other group; NAK family
Chromosomal Location of Human Ortholog: 4q21.21
Cellular Component: nucleoplasm
Molecular Function: protein serine/threonine kinase activity; phosphatase regulator activity; ATP binding
Biological Process: regulation of catalytic activity; protein amino acid phosphorylation; regulation of bone mineralization
Research Articles on BMP2K
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Products associated with BMP2K elisa kit
Pathways associated with BMP2K elisa kit
Diseases associated with BMP2K elisa kit
Organs/Tissues associated with BMP2K elisa kit
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