NP_001321.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,098 Da
NCBI Official Full Name
cardiotrophin-1 isoform 1
NCBI Official Synonym Full Names
cardiotrophin 1
NCBI Official Synonym Symbols
NCBI Protein Information
cardiotrophin-1
UniProt Protein Name
Cardiotrophin-1
UniProt Synonym Gene Names
UniProt Entry Name
CTF1_HUMAN
NCBI Summary for CT-1
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
UniProt Comments for CT-1
CTF1: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytokine
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: extracellular region
Molecular Function: cytokine activity; protein binding
Biological Process: cell proliferation; cell surface receptor linked signal transduction; cell-cell signaling; muscle development; nervous system development; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of Stat3 protein
Research Articles on CT-1
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Products associated with CT-1 elisa kit
Pathways associated with CT-1 elisa kit
Diseases associated with CT-1 elisa kit
Organs/Tissues associated with CT-1 elisa kit
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