NP_077016.2
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,795 Da
NCBI Official Full Name
cation transport regulator-like protein 1 isoform a
NCBI Official Synonym Full Names
ChaC, cation transport regulator homolog 1 (E. coli)
NCBI Protein Information
cation transport regulator-like protein 1; botch; blocks Notch protein; ChaC, cation transport regulator-like 1; gamma-GCT acting on glutathione homolog 1
UniProt Protein Name
Cation transport regulator-like protein 1
UniProt Synonym Protein Names
Blocks Notch protein; Botch
UniProt Synonym Gene Names
UniProt Entry Name
CHAC1_HUMAN
UniProt Comments for CHAC1
CHAC1: Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Belongs to the chaC family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 15q15.1
Cellular Component: trans-Golgi network; cytosol
Molecular Function: protein binding; transferase activity, transferring acyl groups; Notch binding
Biological Process: Notch signaling pathway; neurogenesis; metabolic process; negative regulation of Notch signaling pathway; response to unfolded protein
Research Articles on CHAC1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with CHAC1 elisa kit
Organs/Tissues associated with CHAC1 elisa kit
|