AAI32503.1
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UniProt Related Accession #
Molecular Weight
10,254 Da
NCBI Official Full Name
Chemokine (C-X-C motif) ligand 1
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 1
NCBI Official Synonym Symbols
KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1 [Similar Products]
NCBI Protein Information
growth-regulated alpha protein; KC/GR)-alpha; KC/GRO-alpha; GRO1 oncogene; alpha-chemokine; secretory protein N51; C-X-C motif chemokine 1; platelet-derived growth factor-inducible protein KC
UniProt Protein Name
Growth-regulated alpha protein
UniProt Synonym Protein Names
C-X-C motif chemokine 1; Platelet-derived growth factor-inducible protein KC; Secretory protein N51Cleaved into the following chain:KC(5-72)Alternative name(s):Hematopoietic synergistic factor; HSF; KC-T
UniProt Synonym Gene Names
UniProt Entry Name
GROA_MOUSE
NCBI Summary for CXCL1
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]
UniProt Comments for CXCL1
CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted
Cellular Component: extracellular space; cell; extracellular region; cytosol
Molecular Function: growth factor activity; chemokine activity; CXCR chemokine receptor binding; cytokine activity
Biological Process: neutrophil chemotaxis; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; response to molecule of bacterial origin; positive regulation of superoxide release; positive regulation of potassium ion transport; positive regulation of leukocyte chemotaxis; immune response; response to lipopolysaccharide; inflammatory response; acute inflammatory response; regulation of cell proliferation
Research Articles on CXCL1
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Pathways associated with CXCL1 elisa kit
Diseases associated with CXCL1 elisa kit
Organs/Tissues associated with CXCL1 elisa kit
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