NP_036204.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,560 Da
NCBI Official Full Name
complement component C1q receptor
NCBI Official Synonym Full Names
CD93 molecule
NCBI Official Synonym Symbols
C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1 [Similar Products]
NCBI Protein Information
complement component C1q receptor; C1qR; CD93 antigen; C1q receptor 1; C1q/MBL/SPA receptor; matrix-remodelling associated 4; matrix-remodeling-associated protein 4; complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1
UniProt Protein Name
Complement component C1q receptor
UniProt Synonym Protein Names
C1q/MBL/SPA receptor; C1qR; C1qR(p); C1qRp; CDw93; Complement component 1 q subcomponent receptor 1; Matrix-remodeling-associated protein 4
UniProt Synonym Gene Names
UniProt Entry Name
C1QR1_HUMAN
NCBI Summary for C1QR1
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]
UniProt Comments for C1QR1
CD93: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component: cell surface; cytoplasmic membrane-bound vesicle; integral to membrane; plasma membrane
Molecular Function: protein binding; complement component C1q binding; calcium ion binding; receptor activity; carbohydrate binding
Biological Process: macrophage activation; cell-cell adhesion; viral reproduction; phagocytosis
Research Articles on C1QR1
Precautions
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Diseases associated with C1QR1 elisa kit
Organs/Tissues associated with C1QR1 elisa kit
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