NP_001156598.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
91,391 Da
NCBI Official Full Name
conserved oligomeric Golgi complex subunit 5
NCBI Official Synonym Full Names
component of oligomeric golgi complex 5
NCBI Official Synonym Symbols
GTC90; C87247; D18362; GOLTC1; 5430405C01Rik [Similar Products]
NCBI Protein Information
conserved oligomeric Golgi complex subunit 5; COG complex subunit 5
UniProt Protein Name
Conserved oligomeric Golgi complex subunit 5
UniProt Synonym Protein Names
Component of oligomeric Golgi complex 5
UniProt Synonym Gene Names
UniProt Entry Name
COG5_MOUSE
UniProt Comments for COG5
COG5: Required for normal Golgi function. Defects in COG5 are the cause of congenital disorder of glycosylation type 2I (CDG2I). A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. Congenital disorder of glycosylation type 2I is characterized by mild neurological impairments. Belongs to the COG5 family. 3 isoforms of the human protein are produced by alternative splicing.
Cellular Component: nucleoplasm; Golgi apparatus; membrane; cytoplasm; Golgi transport complex
Biological Process: intra-Golgi vesicle-mediated transport; protein transport; transport; inter-Golgi cisterna vesicle-mediated transport
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Products associated with COG5 elisa kit
Diseases associated with COG5 elisa kit
Organs/Tissues associated with COG5 elisa kit
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