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CAND1 elisa kit :: Bovine Cullin-associated NEDD8-dissociated protein 1 (CAND1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7210215 CAND1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cullin-associated NEDD8-dissociated protein 1 (CAND1), ELISA Kit

 Also Known As   

Bovine Cullin-associated NEDD8-dissociated protein 1 (CAND1) ELISA Kit

 Product Gene Name   

CAND1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    607727
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CAND1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CAND1 purchase    MBS7210215 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cullin-associated NEDD8-dissociated protein 1 (CAND1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CAND1. The ELISA analytical biochemical technique of the MBS7210215 kit is based on CAND1 antibody-CAND1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CAND1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CAND1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CAND1 elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for CAND1. It may not necessarily be applicable to this product.
 NCBI GI #    21361794
 NCBI GeneID    55832
 NCBI Accession #    NP_060918.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_018448.3 [Other Products]
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 UniProt Secondary Accession #    O94918; Q6PIY4; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85; B2RAU3 [Other Products]
 UniProt Related Accession #    Q86VP6 [Other Products]
 Molecular Weight    45,539 Da
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 NCBI Official Full Name    cullin-associated NEDD8-dissociated protein 1
 NCBI Official Synonym Full Names    cullin-associated and neddylation-dissociated 1
 NCBI Official Symbol    CAND1 [Similar Products]
 NCBI Official Synonym Symbols   
TIP120; TIP120A
[Similar Products]
 NCBI Protein Information    cullin-associated NEDD8-dissociated protein 1; p120 CAND1; TBP interacting protein; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; cullin-associated and neddylation-dissociated protein 1
 UniProt Protein Name    Cullin-associated NEDD8-dissociated protein 1
 UniProt Synonym Protein Names   
Cullin-associated and neddylation-dissociated protein 1; TBP-interacting protein of 120 kDa A; TBP-interacting protein 120A; p120 CAND1
 UniProt Gene Name    CAND1 [Similar Products]
 UniProt Synonym Gene Names    KIAA0829; TIP120; TIP120A; TBP-interacting protein 120A [Similar Products]
 UniProt Entry Name    CAND1_HUMAN
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 UniProt Comments for CAND1    CAND1: Enhances transcription from various types of promoters. Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins. Binds TBP. Part of a complex that contains CUL1 and RBX1. Binds unneddylated CUL1, but cannot bind CUL1 once it has been neddylated. Binds CUL2, CUL3, CUL4A, CUL4B and CUL5. Belongs to the CAND family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system; Transcription factor

Chromosomal Location of Human Ortholog: 12q14

Cellular Component: nucleoplasm; cullin-RING ubiquitin ligase complex; membrane; cytoplasm; nucleus; ubiquitin ligase complex

Molecular Function: protein binding; TATA-binding protein binding

Biological Process: SCF complex assembly; negative regulation of catalytic activity; protein ubiquitination; positive regulation of transcriptional preinitiation complex assembly; cell differentiation
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 Research Articles on CAND1    1. The Epstein-Barr virus protein BPLF1, is targeted to cullin-RING ubiquitin ligases (CRLs) via the interaction of the conserved helix-2 with helix-23 of cullins, at a site involved in electrostatic interaction with CAND1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with CAND1 elisa kitOrgans/Tissues associated with CAND1 elisa kit
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >2 publications with CAND1 and Lung Neoplasms
 Liver Neoplasms Antibodies  >1 publications with CAND1 and Liver Neoplasms
 Atrophy Antibodies  >1 publications with CAND1 and Atrophy
 Chromosome Aberrations Antibodies  >1 publications with CAND1 and Chromosome Aberrations
 Anemia, Hemolytic Antibodies  >1 publications with CAND1 and Anemia, Hemolytic
 Kidney Diseases Antibodies  >1 publications with CAND1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with CAND1 and Liver
 Vascular Antibodies  >3 publications with CAND1 and Vascular
 Prostate Antibodies  >3 publications with CAND1 and Prostate
 Muscle Antibodies  >2 publications with CAND1 and Muscle
 Lung Antibodies  >2 publications with CAND1 and Lung
 Brain Antibodies  >2 publications with CAND1 and Brain
 Blood Antibodies  >1 publications with CAND1 and Blood
 Heart Antibodies  >1 publications with CAND1 and Heart
 Bone Marrow Antibodies  >1 publications with CAND1 and Bone Marrow
 Bone Antibodies  >1 publications with CAND1 and Bone
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