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CYSLTS elisa kit :: Bovine Cysteinyl Leukotrienes ELISA Kit

Scan QR to view Datasheet Catalog #    MBS024690 CYSLTS elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cysteinyl Leukotrienes (CYSLTS), ELISA Kit

 Also Known As   

Bovine Cysteinyl Leukotrienes ELISA Kit

 Product Gene Name   

CYSLTS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605666
 3D Structure    ModBase 3D Structure for Q9NS75
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 Species Reactivity    Bovine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CYSLTS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CYSLTS purchase    MBS024690 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cysteinyl Leukotrienes (CYSLTS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CYSLTS. The ELISA analytical biochemical technique of the MBS024690 kit is based on CYSLTS antibody-CYSLTS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYSLTS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYSLTS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CYSLTS. It may not necessarily be applicable to this product.
 NCBI GI #    9966851
 NCBI GeneID    57105
 NCBI Accession #    NP_065110.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020377.2 [Other Products]
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 UniProt Primary Accession #    Q9NS75 [Other Products]
 UniProt Secondary Accession #    Q9HCQ2 [Other Products]
 UniProt Related Accession #    Q9NS75 [Other Products]
 Molecular Weight    39,635 Da
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 NCBI Official Full Name    cysteinyl leukotriene receptor 2
 NCBI Official Synonym Full Names    cysteinyl leukotriene receptor 2
 NCBI Official Symbol    CYSLTR2 [Similar Products]
 NCBI Official Synonym Symbols   
HG57; CYSLT2; HPN321; CYSLT2R; KPG_011; hGPCR21; PSEC0146
[Similar Products]
 NCBI Protein Information    cysteinyl leukotriene receptor 2; G protein-coupled receptor; G-protein coupled receptor HG57; G-protein coupled receptor GPCR21; cysteinyl leukotriene CysLT2 receptor
 UniProt Protein Name    Cysteinyl leukotriene receptor 2
 UniProt Synonym Protein Names   
G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321
 UniProt Gene Name    CYSLTR2 [Similar Products]
 UniProt Synonym Gene Names    CYSLT2; CYSLT2R; CysLTR2; hGPCR21 [Similar Products]
 UniProt Entry Name    CLTR2_HUMAN
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 NCBI Summary for CYSLTS    The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CYSLTS    CYSLTR2: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 13q14.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: protein binding; cysteinyl leukotriene receptor activity; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; immune response
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 Research Articles on CYSLTS    1. Suggest that endothelial and nonendothelial CysLT2R niches have separate roles in mediating inflammatory responses in ischemic/perfusion injury.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CYSLTS elisa kitPathways associated with CYSLTS elisa kit
 Reference Product  PubMed Publications
 CYSLTR1 elisa kit  >14 publications with CYSLTS and CYSLTR1
 TBXA2R elisa kit  >3 publications with CYSLTS and TBXA2R
 GPR17 elisa kit  >1 publications with CYSLTS and GPR17
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 Endothelins Pathway antibodies  Endothelins Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Diseases associated with CYSLTS elisa kitOrgans/Tissues associated with CYSLTS elisa kit
 Disease Name  Pubmed Publications
 Asthma Antibodies  >18 publications with CYSLTS and Asthma
 Lung Diseases, Obstructive Antibodies  >15 publications with CYSLTS and Lung Diseases, Obstructive
 Inflammation Antibodies  >7 publications with CYSLTS and Inflammation
 Rhinitis Antibodies  >4 publications with CYSLTS and Rhinitis
 Drug Hypersensitivity Antibodies  >3 publications with CYSLTS and Drug Hypersensitivity
 Asthma, Aspirin-Induced Antibodies  >3 publications with CYSLTS and Asthma, Aspirin-Induced
 Eosinophilia Antibodies  >2 publications with CYSLTS and Eosinophilia
 Urticaria Antibodies  >2 publications with CYSLTS and Urticaria
 Pain Antibodies  >1 publications with CYSLTS and Pain
 Cardiovascular Diseases Antibodies  >1 publications with CYSLTS and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with CYSLTS and Muscle
 Connective Tissue Antibodies  >1 publications with CYSLTS and Connective Tissue
 Placenta Antibodies  >1 publications with CYSLTS and Placenta
 Brain Antibodies  >1 publications with CYSLTS and Brain
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