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Des elisa kit :: Bovine Desmin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS734722
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Desmin, ELISA Kit

★Popular Item★
 Also Known As   

Bovine Desmin ELISA Kit

 Product Gene Name   

Des elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    615325
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 Species Reactivity    Bovine
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 Specificity    This assay has high sensitivity and excellent specificity for detection of DES. No significant cross-reactivity or interference between DES and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between DES and all the analogues, therefore, cross reaction may still exist in some cases.
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 Samples    Serum, plasma, cell culture supernatants, body fluid and tissue homogenate
 Sensitivity    0.1 ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Des elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Des purchase    MBS734722 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Desmin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Des, with an estimated sensitivity of 0.1 ng/mL. The ELISA analytical biochemical technique of the MBS734722 kit is based on Des antibody-Des antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Des antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Des. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cell culture supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for Des elisa kit

   Intended Uses: This DES ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Bovine DES. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
 Product Categories/Family for Des elisa kit    Signal Transduction
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 Typical Testing Data/Standard Curve (for reference only) of Des elisa kit    Des elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS734722. Click to request current manual
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NCBI/Uniprot data below describe general gene information for Des. It may not necessarily be applicable to this product.
 NCBI GI #    55749932
 NCBI GeneID    1674
 NCBI Accession #    NP_001918.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001927.3 [Other Products]
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 UniProt Secondary Accession #    Q15787; Q549R7; Q549R8; Q549R9; Q8IZR1; Q8IZR6; Q8NES2; Q8NEU6; Q8TAC4; Q8TCX2; Q8TD99 [Other Products]
 UniProt Related Accession #    P17661 [Other Products]
 Molecular Weight    53,536 Da
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 NCBI Official Full Name    desmin
 NCBI Official Synonym Full Names    desmin
 NCBI Official Symbol    DES [Similar Products]
 NCBI Official Synonym Symbols   
CSM1; CSM2; LGMD2R
[Similar Products]
 NCBI Protein Information    desmin; mutant desmin p.K241E; intermediate filament protein
 UniProt Protein Name    Desmin
 Protein Family    Desmin
 UniProt Gene Name    DES [Similar Products]
 UniProt Entry Name    DESM_HUMAN
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 NCBI Summary for Des    This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Des    desmin: a class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: intermediate filament; fascia adherens; neuromuscular junction; cytosol; Z disc; sarcolemma

Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; cytoskeletal protein binding

Biological Process: muscle contraction; cytoskeleton organization and biogenesis; regulation of heart contraction; muscle filament sliding

Disease: Cardiomyopathy, Dilated, 1i; Scapuloperoneal Syndrome, Neurogenic, Kaeser Type; Myopathy, Myofibrillar, 1; Muscular Dystrophy, Limb-girdle, Type 2r
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 Research Articles on Des    1. Data suggest that loss of the desmin-p. A120D filament localization at the intercalated disk indicates its clinical arrhythmogenic potential.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Des elisa kitDiseases associated with Des elisa kit
 Products by Pathway  Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >9031 publications with Des and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >8944 publications with Des and Cardiovascular Diseases
 Heart Diseases Antibodies  >5241 publications with Des and Heart Diseases
 Carcinoma Antibodies  >3593 publications with Des and Carcinoma
 Inflammation Antibodies  >3397 publications with Des and Inflammation
 Pain Antibodies  >2900 publications with Des and Pain
 Liver Diseases Antibodies  >2353 publications with Des and Liver Diseases
 Thrombosis Antibodies  >2236 publications with Des and Thrombosis
 Disease Models, Animal Antibodies  >2112 publications with Des and Disease Models, Animal
 Adenocarcinoma Antibodies  >1883 publications with Des and Adenocarcinoma
Organs/Tissues associated with Des elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17812 publications with Des and Blood
 Brain Antibodies  >9074 publications with Des and Brain
 Vascular Antibodies  >5509 publications with Des and Vascular
 Muscle Antibodies  >5195 publications with Des and Muscle
 Heart Antibodies  >4944 publications with Des and Heart
 Liver Antibodies  >4699 publications with Des and Liver
 Bone Antibodies  >4131 publications with Des and Bone
 Lung Antibodies  >3231 publications with Des and Lung
 Skin Antibodies  >3199 publications with Des and Skin
 Nerve Antibodies  >2811 publications with Des and Nerve
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