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FBXO45 elisa kit :: Bovine F-box/SPRY domain-containing protein 1 (FBXO45) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7217690 FBXO45 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

F-box/SPRY domain-containing protein 1 (FBXO45), ELISA Kit

 Also Known As   

Bovine F-box/SPRY domain-containing protein 1 (FBXO45) ELISA Kit

 Product Gene Name   

FBXO45 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    609112
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FBXO45 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FBXO45 purchase    MBS7217690 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the F-box/SPRY domain-containing protein 1 (FBXO45) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FBXO45. The ELISA analytical biochemical technique of the MBS7217690 kit is based on FBXO45 antibody-FBXO45 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FBXO45 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FBXO45. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for FBXO45 elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for FBXO45. It may not necessarily be applicable to this product.
 NCBI GI #    157743247
 NCBI GeneID    200933
 NCBI Accession #    NP_001099043.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001105573.1 [Other Products]
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 UniProt Secondary Accession #    A6NF90; D3DXB5 [Other Products]
 UniProt Related Accession #    P0C2W1 [Other Products]
 Molecular Weight    30,633 Da [Similar Products]
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 NCBI Official Full Name    F-box/SPRY domain-containing protein 1
 NCBI Official Synonym Full Names    F-box protein 45
 NCBI Official Symbol    FBXO45 [Similar Products]
 NCBI Official Synonym Symbols   
Fbx45
[Similar Products]
 NCBI Protein Information    F-box/SPRY domain-containing protein 1; hFbxo45; F-box only protein 45
 UniProt Protein Name    F-box/SPRY domain-containing protein 1
 UniProt Synonym Protein Names   
F-box only protein 45; hFbxo45
 UniProt Gene Name    FBXO45 [Similar Products]
 UniProt Synonym Gene Names    FBX45; hFbxo45 [Similar Products]
 UniProt Entry Name    FBSP1_HUMAN
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 NCBI Summary for FBXO45    Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Jan 2011]
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 UniProt Comments for FBXO45    FBXO45: Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation. Belongs to the FBXO45/Fsn family.

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: presynaptic membrane; postsynaptic membrane; postsynaptic density; cell junction

Molecular Function: protein binding

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; anterior commissure morphogenesis; cerebral cortex tangential migration; protein ubiquitination during ubiquitin-dependent protein catabolic process; neuron migration; protein ubiquitination; cerebral cortex radially oriented cell migration; corticospinal tract morphogenesis; response to DNA damage stimulus
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 Research Articles on FBXO45    1. FBXO45 promotes the proteasome-dependent degradation of p73.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FBXO45 elisa kitDiseases associated with FBXO45 elisa kit
 Reference Product  PubMed Publications
 MYCBP2 elisa kit  >4 publications with FBXO45 and MYCBP2
 SKP1 elisa kit  >2 publications with FBXO45 and SKP1
 FBXL18 elisa kit  >1 publications with FBXO45 and FBXL18
 UNC13A elisa kit  >1 publications with FBXO45 and UNC13A
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >1 publications with FBXO45 and Mental Disorders
 Kidney Neoplasms Antibodies  >1 publications with FBXO45 and Kidney Neoplasms
 Neurobehavioral Manifestations Antibodies  >1 publications with FBXO45 and Neurobehavioral Manifestations
 Learning Disorders Antibodies  >1 publications with FBXO45 and Learning Disorders
Organs/Tissues associated with FBXO45 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with FBXO45 and Brain
 Kidney Antibodies  >1 publications with FBXO45 and Kidney
 Liver Antibodies  >1 publications with FBXO45 and Liver
 Prostate Antibodies  >1 publications with FBXO45 and Prostate
 Parathyroid Antibodies  >1 publications with FBXO45 and Parathyroid
 Lung Antibodies  >1 publications with FBXO45 and Lung
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