NM_019113.3
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,300 Da
NCBI Official Full Name
fibroblast growth factor 21
NCBI Official Synonym Full Names
fibroblast growth factor 21
NCBI Protein Information
fibroblast growth factor 21
UniProt Protein Name
Fibroblast growth factor 21
UniProt Synonym Gene Names
UniProt Entry Name
FGF21_HUMAN
NCBI Summary for FGF21
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016]
UniProt Comments for FGF21
FGF21: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Belongs to the heparin-binding growth factors family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: extracellular region
Molecular Function: protein binding
Biological Process: cell-cell signaling; positive regulation of glucose import; signal transduction
Research Articles on FGF21
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Products associated with FGF21 elisa kit
Pathways associated with FGF21 elisa kit
Diseases associated with FGF21 elisa kit
Organs/Tissues associated with FGF21 elisa kit
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