NP_000502.4
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,740 Da
NCBI Official Full Name
galactoside 2-alpha-L-fucosyltransferase 2
NCBI Official Synonym Full Names
fucosyltransferase 2 (secretor status included)
NCBI Protein Information
galactoside 2-alpha-L-fucosyltransferase 2; alpha(1,2)FT2; alpha(1,2)FT 2; secretor factor; alpha (1,2) fucosyltransferase; secretor blood group alpha-2-fucosyltransferase; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2
UniProt Protein Name
Galactoside 2-alpha-L-fucosyltransferase 2
UniProt Synonym Protein Names
Alpha(1,2)FT 2; Fucosyltransferase 2; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2; SE2; Secretor blood group alpha-2-fucosyltransferase; Secretor factor; Se
UniProt Synonym Gene Names
UniProt Entry Name
FUT2_HUMAN
NCBI Summary for FUT2
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FUT2
FUT2: Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 11 family. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase; Membrane protein, integral; EC 2.4.1.69; Glycan Metabolism - glycosphingolipid biosynthesis - globo series
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: Golgi apparatus; integral to membrane
Molecular Function: galactoside 2-alpha-L-fucosyltransferase activity; fucosyltransferase activity
Biological Process: carbohydrate metabolic process; protein amino acid glycosylation; L-fucose catabolic process
Disease: Vitamin B12 Plasma Level Quantitative Trait Locus 1
Research Articles on FUT2
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Products associated with FUT2 elisa kit
Pathways associated with FUT2 elisa kit
Diseases associated with FUT2 elisa kit
Organs/Tissues associated with FUT2 elisa kit
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