EAW68880.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
80,474 Da
NCBI Official Full Name
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV), isoform CRA_b
NCBI Official Synonym Full Names
glucan (1,4-alpha-), branching enzyme 1
NCBI Protein Information
1,4-alpha-glucan-branching enzyme; brancher enzyme; glycogen branching enzyme; glycogen-branching enzyme; amylo-(1,4 to 1,6) transglucosidase; amylo-(1,4 to 1,6) transglycosylase
UniProt Protein Name
1,4-alpha-glucan-branching enzyme
UniProt Synonym Protein Names
Brancher enzyme; Glycogen-branching enzyme
UniProt Entry Name
GLGB_HUMAN
NCBI Summary for Gamma secretase
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease). [provided by RefSeq, Jul 2008]
UniProt Comments for Gamma secretase
GBE1: a monomeric enzyme that functions in glycogen symthesis by catalyzing the formation of alpha 1,6- glucosidic linkages.Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells. It is most highly expressed in liver and muscle. Deficiency can result in glycogen storage disease IV (Andersen's disease).
Protein type: Carbohydrate Metabolism - starch and sucrose; Transferase; EC 2.4.1.18
Chromosomal Location of Human Ortholog: 3p12.3
Cellular Component: cytosol
Molecular Function: cation binding; 1,4-alpha-glucan branching enzyme activity; hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process: glycogen metabolic process; generation of precursor metabolites and energy; glycogen biosynthetic process; carbohydrate metabolic process; glucose metabolic process; pathogenesis
Disease: Polyglucosan Body Disease, Adult Form; Glycogen Storage Disease Iv
Research Articles on Gamma secretase
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Products associated with Gamma secretase elisa kit
Pathways associated with Gamma secretase elisa kit
Diseases associated with Gamma secretase elisa kit
Organs/Tissues associated with Gamma secretase elisa kit
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