NP_001135840.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,745 Da
NCBI Official Full Name
glutathione S-transferase Mu 2 isoform 2
NCBI Official Synonym Full Names
glutathione S-transferase mu 2 (muscle)
NCBI Protein Information
glutathione S-transferase Mu 2; GST, muscle; GST class-mu 2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-aryltransferase M2; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; S-(hydroxyalkyl)glutathione lyase M2; glutathione S-transferase M2 (muscle)
UniProt Protein Name
Glutathione S-transferase Mu 2
UniProt Synonym Protein Names
GST class-mu 2; GSTM2-2
UniProt Synonym Gene Names
UniProt Entry Name
GSTM2_HUMAN
NCBI Summary for GT
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq, Jul 2008]
UniProt Comments for GT
GSTM2: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family.
Protein type: Transferase; Motility/polarity/chemotaxis; EC 2.5.1.18
Chromosomal Location of Human Ortholog: 1p13.3
Cellular Component: sarcoplasmic reticulum; cytoplasm; cytosol
Molecular Function: enzyme binding; protein homodimerization activity; glutathione transferase activity; glutathione binding; receptor binding
Biological Process: regulation of skeletal muscle contraction via regulation of the release of sequestered calcium ion; glutathione metabolic process; nitrobenzene metabolic process; xenobiotic metabolic process; xenobiotic catabolic process
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Products associated with GT elisa kit
Pathways associated with GT elisa kit
Diseases associated with GT elisa kit
Organs/Tissues associated with GT elisa kit
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