AAI08696.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
84,660 Da
NCBI Official Full Name
HSP90AA1 protein
NCBI Official Synonym Full Names
heat shock protein 90kDa alpha (cytosolic), class A member 1
NCBI Official Synonym Symbols
EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4 [Similar Products]
NCBI Protein Information
heat shock protein HSP 90-alpha; HSP 86; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kDa protein 1, alpha; renal carcinoma antigen NY-REN-38; heat shock 90kD protein, alpha-like 4; epididymis luminal secretory protein 52; heat shock 90kD protein 1, alpha-like 4
UniProt Protein Name
Heat shock protein HSP 90-alpha
UniProt Synonym Protein Names
Heat shock 86 kDa; HSP 86; HSP86; Renal carcinoma antigen NY-REN-38
UniProt Synonym Gene Names
UniProt Entry Name
HS90A_HUMAN
NCBI Summary for HSP90aA1
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
UniProt Comments for HSP90aA1
HSP90A: a molecular chaperone of the heat shock protein 90 family. Has ATPase activity. Known to interact with a wide variety of proteins including steroid hormone receptors, neuropeptide Y, FKBP51/54, and FKBP52. G protein-coupled receptor kinases are stabilized by interacting with HSP 90. Hsp70 and Hsp90 promote tau solubility and tau binding to microtubules, reducing insoluble tau phosphorylation of tau.
Protein type: Chaperone; Heat shock protein
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: nucleoplasm; membrane; mitochondrion; cytoplasm; extracellular region; melanosome; plasma membrane; cytosol; nucleus
Molecular Function: identical protein binding; protein binding; protein homodimerization activity; TPR domain binding; ATPase activity; unfolded protein binding; nitric-oxide synthase regulator activity; nucleotide binding; ATP binding
Biological Process: receptor-mediated endocytosis; axon guidance; positive regulation of nitric oxide biosynthetic process; organelle organization and biogenesis; signal transduction; protein import into mitochondrial outer membrane; nitric oxide metabolic process; response to unfolded protein; mitochondrial transport; innate immune response; protein refolding; mitotic cell cycle; regulation of nitric-oxide synthase activity; vascular endothelial growth factor receptor signaling pathway; chaperone-mediated protein complex assembly; G2/M transition of mitotic cell cycle
Research Articles on HSP90aA1
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Pathways associated with HSP90aA1 elisa kit
Diseases associated with HSP90aA1 elisa kit
Organs/Tissues associated with HSP90aA1 elisa kit
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