NP_036617.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,495 Da
NCBI Official Full Name
hyaluronan mediated motility receptor isoform c
NCBI Official Synonym Full Names
hyaluronan-mediated motility receptor (RHAMM)
NCBI Protein Information
hyaluronan mediated motility receptor; receptor for hyaluronan-mediated motility; intracellular hyaluronic acid-binding protein
UniProt Protein Name
Hyaluronan mediated motility receptor
UniProt Synonym Protein Names
Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility; CD_antigen: CD168
UniProt Synonym Gene Names
UniProt Entry Name
HMMR_HUMAN
NCBI Summary for HMMR/CD168
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]
UniProt Comments for HMMR/CD168
HMMR: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 5q34
Cellular Component: cell surface; membrane; cytoplasm; plasma membrane
Molecular Function: hyaluronic acid binding
Biological Process: glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis; hyaluronan metabolic process; hyaluronan catabolic process
Disease: Breast Cancer
Research Articles on HMMR/CD168
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Products associated with HMMR/CD168 elisa kit
Pathways associated with HMMR/CD168 elisa kit
Diseases associated with HMMR/CD168 elisa kit
Organs/Tissues associated with HMMR/CD168 elisa kit
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