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IL2Ralpha elisa kit :: Bovine Interleukin 2 Receptor Alpha ELISA Kit

Scan QR to view Datasheet Catalog #    MBS075418 IL2Ralpha elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 2 Receptor Alpha (IL2Ralpha), ELISA Kit

 Also Known As   

Bovine Interleukin 2 Receptor Alpha ELISA Kit

 Product Gene Name   

IL2Ralpha elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    601070
 3D Structure    ModBase 3D Structure for Q13261
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL2Ralpha elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL2Ralpha purchase    MBS075418 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 2 Receptor Alpha (IL2Ralpha) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL2Ralpha. The ELISA analytical biochemical technique of the MBS075418 kit is based on IL2Ralpha antibody-IL2Ralpha antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL2Ralpha antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL2Ralpha. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IL2Ralpha. It may not necessarily be applicable to this product.
 NCBI GI #    294712549
 NCBI GeneID    3601
 NCBI Accession #    NP_751950.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_172200.2 [Other Products]
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 UniProt Primary Accession #    Q13261 [Other Products]
 UniProt Secondary Accession #    Q5JVA1; Q5JVA2; Q5JVA4; Q6B0J2; Q7LDR4; Q7Z609; B4E2C2 [Other Products]
 UniProt Related Accession #    Q13261 [Other Products]
 Molecular Weight    28,233 Da
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 NCBI Official Full Name    interleukin-15 receptor subunit alpha isoform 2
 NCBI Official Synonym Full Names    interleukin 15 receptor, alpha
 NCBI Official Symbol    IL15RA [Similar Products]
 NCBI Official Synonym Symbols   
CD215
[Similar Products]
 NCBI Protein Information    interleukin-15 receptor subunit alpha; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8
 UniProt Protein Name    Interleukin-15 receptor subunit alpha
 UniProt Gene Name    IL15RA [Similar Products]
 UniProt Synonym Gene Names    IL-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; sIL-15 receptor subunit alpha; sIL-15R-alpha; sIL-15RA [Similar Products]
 UniProt Entry Name    I15RA_HUMAN
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 NCBI Summary for IL2Ralpha    This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]
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 UniProt Comments for IL2Ralpha    IL15RA: High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves STAT3, STAT5, STAT6, JAK2 and SYK. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: Golgi membrane; extracellular space; endoplasmic reticulum membrane; nuclear membrane; cytoplasmic vesicle membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; signal transducer activity; protein binding

Biological Process: cell proliferation; cytokine and chemokine mediated signaling pathway; signal transduction
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 Research Articles on IL2Ralpha    1. Data indicate that tumor necrosis factor-alpha (TNF) abolishes nuclear localization of IL-15 and IL-15Ralpha by acting on chromosomal region maintenance 1 (CRM1), and it facilitates exocytosis of IL-15 with the involvement of ADP-ribosylation factor 6 (ARF6).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL2Ralpha elisa kitPathways associated with IL2Ralpha elisa kit
 Reference Product  PubMed Publications
 IL15 elisa kit  >232 publications with IL2Ralpha and IL15
 IL2RB elisa kit  >23 publications with IL2Ralpha and IL2RB
 IL2RG elisa kit  >12 publications with IL2Ralpha and IL2RG
 JAK1 elisa kit  >7 publications with IL2Ralpha and JAK1
 JAK3 elisa kit  >7 publications with IL2Ralpha and JAK3
 JAK2 elisa kit  >4 publications with IL2Ralpha and JAK2
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 TCR Signaling Pathway antibodies  TCR Signaling Pathway Diagram
Organs/Tissues associated with IL2Ralpha elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >169 publications with IL2Ralpha and Blood
 Spleen Antibodies  >18 publications with IL2Ralpha and Spleen
 Lung Antibodies  >14 publications with IL2Ralpha and Lung
 Intestine Antibodies  >11 publications with IL2Ralpha and Intestine
 Skin Antibodies  >8 publications with IL2Ralpha and Skin
 Liver Antibodies  >6 publications with IL2Ralpha and Liver
 Brain Antibodies  >5 publications with IL2Ralpha and Brain
 Uterus Antibodies  >5 publications with IL2Ralpha and Uterus
 Eye Antibodies  >3 publications with IL2Ralpha and Eye
 Prostate Antibodies  >3 publications with IL2Ralpha and Prostate
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