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LOX elisa kit :: Bovine Lysyl Oxidase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS020463 LOX elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lysyl Oxidase (LOX), ELISA Kit

 Also Known As   

Bovine Lysyl Oxidase ELISA Kit

 Product Gene Name   

LOX elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 5; NC_000005.9 (121398890..121414055, complement). Location: 5q23.2
 OMIM    153455
 3D Structure    ModBase 3D Structure for P28300
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 Species Reactivity    Bovine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LOX elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LOX purchase    MBS020463 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Lysyl Oxidase (LOX) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LOX. The ELISA analytical biochemical technique of the MBS020463 kit is based on LOX antibody-LOX antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LOX antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LOX. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for LOX. It may not necessarily be applicable to this product.
 NCBI GI #    257065
 NCBI GeneID    4015
 NCBI Accession #    AAB23549.1 [Other Products]
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 UniProt Primary Accession #    P28300 [Other Products]
 UniProt Secondary Accession #    Q5FWF0; B2R5Q3 [Other Products]
 UniProt Related Accession #    P28300 [Other Products]
 Molecular Weight    46,944 Da
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 NCBI Official Full Name    lysyl oxidase
 NCBI Official Synonym Full Names    lysyl oxidase
 NCBI Official Symbol    LOX [Similar Products]
 NCBI Protein Information    protein-lysine 6-oxidase
 UniProt Protein Name    Protein-lysine 6-oxidase
 UniProt Synonym Protein Names   
Lysyl oxidase
 Protein Family    Lysyl oxidase
 UniProt Gene Name    LOX [Similar Products]
 UniProt Entry Name    LYOX_HUMAN
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 NCBI Summary for LOX    The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
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 UniProt Comments for LOX    LOX: Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression. Belongs to the lysyl oxidase family.

Protein type: Secreted; EC 1.4.3.13; Secreted, signal peptide; Oxidoreductase

Chromosomal Location of Human Ortholog: 5q23.2

Cellular Component: extracellular space; proteinaceous extracellular matrix; collagen; extracellular region; nucleus

Molecular Function: protein binding; copper ion binding; protein-lysine 6-oxidase activity

Biological Process: response to drug; elastic fiber assembly; blood vessel development; extracellular matrix organization and biogenesis; collagen fibril organization; wound healing; response to steroid hormone stimulus; protein modification process; lung development

Disease: Cutis Laxa, Autosomal Recessive, Type Ia
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 Research Articles on LOX    1. conclude that the ECM modulating enzyme LOX is associated with amyloid-beta pathology in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis--Dutch type.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LOX elisa kitPathways associated with LOX elisa kit
 Reference Product  PubMed Publications
 ALOX5 elisa kit  >325 publications with LOX and ALOX5
 SRC elisa kit  >27 publications with LOX and SRC
 FGF2 elisa kit  >12 publications with LOX and FGF2
 FBLN5 elisa kit  >6 publications with LOX and FBLN5
 FBN1 elisa kit  >2 publications with LOX and FBN1
 FN1 elisa kit  >2 publications with LOX and FN1
 TGFBI elisa kit  >1 publications with LOX and TGFBI
 Products by Pathway  Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Crosslinking Of Collagen Fibrils Pathway antibodies  Crosslinking Of Collagen Fibrils Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with LOX elisa kitOrgans/Tissues associated with LOX elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >705 publications with LOX and Neoplasms
 Cardiovascular Diseases Antibodies  >468 publications with LOX and Cardiovascular Diseases
 Inflammation Antibodies  >454 publications with LOX and Inflammation
 Disease Models, Animal Antibodies  >315 publications with LOX and Disease Models, Animal
 Necrosis Antibodies  >186 publications with LOX and Necrosis
 Heart Diseases Antibodies  >144 publications with LOX and Heart Diseases
 Drug Toxicity Antibodies  >141 publications with LOX and Drug Toxicity
 Neoplasms, Experimental Antibodies  >137 publications with LOX and Neoplasms, Experimental
 Brain Diseases Antibodies  >124 publications with LOX and Brain Diseases
 Hypertension Antibodies  >111 publications with LOX and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >604 publications with LOX and Vascular
 Muscle Antibodies  >332 publications with LOX and Muscle
 Brain Antibodies  >283 publications with LOX and Brain
 Lung Antibodies  >233 publications with LOX and Lung
 Heart Antibodies  >209 publications with LOX and Heart
 Liver Antibodies  >200 publications with LOX and Liver
 Bone Antibodies  >180 publications with LOX and Bone
 Skin Antibodies  >156 publications with LOX and Skin
 Kidney Antibodies  >140 publications with LOX and Kidney
 Embryonic Tissue Antibodies  >133 publications with LOX and Embryonic Tissue
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