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NEFM elisa kit :: Bovine Neurofilament medium polypeptide (NEFM) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7208228 NEFM elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neurofilament medium polypeptide (NEFM), ELISA Kit

 Also Known As   

Bovine Neurofilament medium polypeptide (NEFM) ELISA Kit

 Product Gene Name   

NEFM elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    162250
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NEFM elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NEFM purchase    MBS7208228 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neurofilament medium polypeptide (NEFM) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NEFM. The ELISA analytical biochemical technique of the MBS7208228 kit is based on NEFM antibody-NEFM antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NEFM antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NEFM. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for NEFM elisa kit    Neuroscience
NCBI/Uniprot data below describe general gene information for NEFM. It may not necessarily be applicable to this product.
 NCBI GI #    281185500
 NCBI GeneID    4741
 NCBI Accession #    P07197.3 [Other Products]
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 UniProt Secondary Accession #    Q4QRK6; B4DGN2; E9PBF7 [Other Products]
 UniProt Related Accession #    P07197 [Other Products]
 Molecular Weight    59,599 Da
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 NCBI Official Full Name    Neurofilament medium polypeptide
 NCBI Official Synonym Full Names    neurofilament, medium polypeptide
 NCBI Official Symbol    NEFM [Similar Products]
 NCBI Official Synonym Symbols   
NFM; NEF3; NF-M
[Similar Products]
 NCBI Protein Information    neurofilament medium polypeptide; neurofilament 3; 160 kDa neurofilament protein; neurofilament triplet M protein; neurofilament-3 (150 kD medium); neurofilament, medium polypeptide 150kDa
 UniProt Protein Name    Neurofilament medium polypeptide
 UniProt Synonym Protein Names   
160 kDa neurofilament protein; Neurofilament 3; Neurofilament triplet M protein
 Protein Family    Neurofilament medium polypeptide
 UniProt Gene Name    NEFM [Similar Products]
 UniProt Synonym Gene Names    NEF3; NFM; NF-M [Similar Products]
 UniProt Entry Name    NFM_HUMAN
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 NCBI Summary for NEFM    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
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 UniProt Comments for NEFM    NFM: a neurofilament intermediate filament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The levels of phosphorylation are altered developmentally and coincident with a change in the neurofilament function.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: axon; neurofilament; neuromuscular junction

Molecular Function: protein binding; structural constituent of cytoskeleton; microtubule binding

Biological Process: neurofilament bundle assembly; axon cargo transport; regulation of axon diameter; microtubule cytoskeleton organization and biogenesis
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 Research Articles on NEFM    1. There was a strongly elevated reactivity against neurofilament medium in a subset of schizophrenia patients compared to controls.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NEFM elisa kitPathways associated with NEFM elisa kit
 Reference Product  PubMed Publications
 NEFL elisa kit  >2 publications with NEFM and NEFL
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
Diseases associated with NEFM elisa kitOrgans/Tissues associated with NEFM elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with NEFM and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with NEFM and Brain Diseases
 Necrosis Antibodies  >1 publications with NEFM and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with NEFM and Brain
 Nerve Antibodies  >2 publications with NEFM and Nerve
 Embryonic Tissue Antibodies  >1 publications with NEFM and Embryonic Tissue
 Muscle Antibodies  >1 publications with NEFM and Muscle
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