NP_065176.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
195,040 Da
NCBI Official Full Name
neuron navigator 1 isoform 1
NCBI Official Synonym Full Names
neuron navigator 1
NCBI Protein Information
neuron navigator 1
UniProt Protein Name
Neuron navigator 1
UniProt Synonym Protein Names
Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1
UniProt Synonym Gene Names
UniProt Entry Name
NAV1_HUMAN
NCBI Summary for NAV1
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
UniProt Comments for NAV1
NAV1: May be involved in neuronal migration. Belongs to the Nav/unc-53 family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q32.3
Cellular Component: cytoplasm; microtubule
Molecular Function: protein binding
Biological Process: microtubule bundle formation; neuron migration
Research Articles on NAV1
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