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P-PKC elisa kit :: Bovine Phospho Protein Kinase C ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006353 P-PKC elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Phospho Protein Kinase C (P-PKC), ELISA Kit

 Also Known As   

Bovine Phospho Protein Kinase C ELISA Kit

 Product Gene Name   

P-PKC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    190090
 3D Structure    ModBase 3D Structure for P12931
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 Species Reactivity    Bovine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of P-PKC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for P-PKC purchase    MBS006353 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Phospho Protein Kinase C (P-PKC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing P-PKC. The ELISA analytical biochemical technique of the MBS006353 kit is based on P-PKC antibody-P-PKC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect P-PKC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, P-PKC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for P-PKC. It may not necessarily be applicable to this product.
 NCBI GI #    125711
 NCBI GeneID    6714
 NCBI Accession #    P12931.3 [Other Products]
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 UniProt Primary Accession #    P12931 [Other Products]
 UniProt Secondary Accession #    Q76P87; Q86VB9; Q9H5A8; E1P5V4 [Other Products]
 UniProt Related Accession #    P12931 [Other Products]
 Molecular Weight    59,835 Da
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 NCBI Official Full Name    Proto-oncogene tyrosine-protein kinase Src
 NCBI Official Synonym Full Names    SRC proto-oncogene, non-receptor tyrosine kinase
 NCBI Official Symbol    SRC [Similar Products]
 NCBI Official Synonym Symbols   
ASV; SRC1; c-SRC; p60-Src
[Similar Products]
 NCBI Protein Information    proto-oncogene tyrosine-protein kinase Src; proto-oncogene c-Src; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; protooncogene SRC, Rous sarcoma; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
 UniProt Protein Name    Proto-oncogene tyrosine-protein kinase Src
 UniProt Synonym Protein Names   
Proto-oncogene c-Src; pp60c-src
 UniProt Gene Name    SRC [Similar Products]
 UniProt Synonym Gene Names    SRC1; p60-Src [Similar Products]
 UniProt Entry Name    SRC_HUMAN
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 NCBI Summary for P-PKC    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for P-PKC    Src: proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme. Two alternatively spliced isoforms have been described.

Protein type: Protein kinase, tyrosine (non-receptor); Kinase, protein; Protein kinase, TK; EC 2.7.10.2; Oncoprotein; TK group; Src family

Chromosomal Location of Human Ortholog: 20q12-q13

Cellular Component: neuron projection; mitochondrion; lysosome; postsynaptic density; actin filament; caveola; cytosol; extrinsic to internal side of plasma membrane; perinuclear region of cytoplasm; mitochondrial inner membrane; late endosome; cytoplasm; plasma membrane; nucleus

Molecular Function: protein C-terminus binding; ephrin receptor binding; non-membrane spanning protein tyrosine kinase activity; phosphoprotein binding; insulin receptor binding; protein kinase activity; integrin binding; protein binding; enzyme binding; SH3/SH2 adaptor activity; protein kinase C binding; protein-tyrosine kinase activity; heme binding; estrogen receptor binding; SH2 domain binding; kinase activity; ATP binding; hormone receptor binding; receptor binding

Biological Process: oogenesis; regulation of estrogen receptor signaling pathway; positive regulation of cyclin-dependent protein kinase activity; estrogen receptor signaling pathway; central nervous system development; progesterone receptor signaling pathway; nerve growth factor receptor signaling pathway; viral reproduction; regulation of cell cycle; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; uterus development; negative regulation of mitochondrial depolarization; negative regulation of protein homooligomerization; positive regulation of MAP kinase activity; cell-cell adhesion; transforming growth factor beta receptor signaling pathway; response to electrical stimulus; cell adhesion; bone resorption; response to drug; platelet activation; fibroblast growth factor receptor signaling pathway; activation of protein kinase B; response to virus; transcytosis; positive regulation of integrin activation; positive regulation of protein amino acid autophosphorylation; cellular response to insulin stimulus; response to mechanical stimulus; T cell costimulation; regulation of vascular permeability; negative regulation of transcription, DNA-dependent; leukocyte migration; negative regulation of apoptosis; axon guidance; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; platelet-derived growth factor receptor signaling pathway; negative regulation of caspase activity; positive regulation of smooth muscle cell migration; signal transduction; regulation of cell-cell adhesion; forebrain development; ephrin receptor signaling pathway; integrin-mediated signaling pathway; epidermal growth factor receptor signaling pathway; response to nutrient levels; regulation of bone resorption; negative regulation of focal adhesion formation; signal complex assembly; positive regulation of phosphoinositide 3-kinase activity; response to mineralocorticoid stimulus; cell cycle; regulation of cell proliferation; cell proliferation; positive regulation of protein kinase B signaling cascade; peptidyl-serine phosphorylation; response to hydrogen peroxide; regulation of protein binding; Ras protein signal transduction; stress fiber formation; innate immune response; positive regulation of insulin receptor signaling pathway; response to acidity; blood coagulation; vascular endothelial growth factor receptor signaling pathway; positive regulation of cytokine secretion
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 Research Articles on P-PKC    1. Data indicate that inhibition of Src activity induces persistent activation of ataxia telangiectasia mutated (ATM)- and Rad3-related (ATR) and check point kinase 1 (Chk1).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with P-PKC elisa kitPathways associated with P-PKC elisa kit
 Reference Product  PubMed Publications
 EGFR elisa kit  >1194 publications with P-PKC and EGFR
 STAT3 elisa kit  >772 publications with P-PKC and STAT3
 PTK2 elisa kit  >605 publications with P-PKC and PTK2
 CBL elisa kit  >486 publications with P-PKC and CBL
 BCAR1 elisa kit  >165 publications with P-PKC and BCAR1
 CAV1 elisa kit  >124 publications with P-PKC and CAV1
 VDR elisa kit  >87 publications with P-PKC and VDR
 KHDRBS1 elisa kit  >82 publications with P-PKC and KHDRBS1
 PTPN1 elisa kit  >65 publications with P-PKC and PTPN1
 ESR1 elisa kit  >10 publications with P-PKC and ESR1
 Products by Pathway  Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Angiogenesis Pathway antibodies  Angiogenesis Pathway Diagram
Diseases associated with P-PKC elisa kitOrgans/Tissues associated with P-PKC elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6554 publications with P-PKC and Neoplasms
 Breast Neoplasms Antibodies  >1032 publications with P-PKC and Breast Neoplasms
 Inflammation Antibodies  >794 publications with P-PKC and Inflammation
 Disease Models, Animal Antibodies  >776 publications with P-PKC and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >753 publications with P-PKC and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >736 publications with P-PKC and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >657 publications with P-PKC and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >603 publications with P-PKC and Neoplasm Metastasis
 Necrosis Antibodies  >592 publications with P-PKC and Necrosis
 Neoplasm Invasiveness Antibodies  >526 publications with P-PKC and Neoplasm Invasiveness
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5071 publications with P-PKC and Blood
 Brain Antibodies  >2005 publications with P-PKC and Brain
 Muscle Antibodies  >1563 publications with P-PKC and Muscle
 Bone Antibodies  >1311 publications with P-PKC and Bone
 Kidney Antibodies  >1124 publications with P-PKC and Kidney
 Nerve Antibodies  >1042 publications with P-PKC and Nerve
 Lung Antibodies  >1002 publications with P-PKC and Lung
 Liver Antibodies  >854 publications with P-PKC and Liver
 Embryonic Tissue Antibodies  >523 publications with P-PKC and Embryonic Tissue
 Prostate Antibodies  >481 publications with P-PKC and Prostate
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