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PLCzeta1 elisa kit :: Bovine Phospholipase C Zeta 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS079224 PLCzeta1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Phospholipase C Zeta 1 (PLCzeta1), ELISA Kit

 Also Known As   

Bovine Phospholipase C Zeta 1 ELISA Kit

 Product Gene Name   

PLCzeta1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    608075
 3D Structure    ModBase 3D Structure for Q86YW0
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PLCzeta1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PLCzeta1 purchase    MBS079224 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Phospholipase C Zeta 1 (PLCzeta1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLCzeta1. The ELISA analytical biochemical technique of the MBS079224 kit is based on PLCzeta1 antibody-PLCzeta1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLCzeta1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLCzeta1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PLCzeta1. It may not necessarily be applicable to this product.
 NCBI GI #    119616796
 NCBI GeneID    89869
 NCBI Accession #    EAW96390.1 [Other Products]
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 UniProt Primary Accession #    Q86YW0 [Other Products]
 UniProt Secondary Accession #    Q08AQ7; Q96J70 [Other Products]
 UniProt Related Accession #    Q86YW0 [Other Products]
 Molecular Weight    70,411 Da
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 NCBI Official Full Name    phospholipase C, zeta 1, isoform CRA_c
 NCBI Official Synonym Full Names    phospholipase C, zeta 1
 NCBI Official Symbol    PLCZ1 [Similar Products]
 NCBI Official Synonym Symbols   
PLCzeta; NYD-SP27; PLC-zeta-1
[Similar Products]
 NCBI Protein Information    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; PI-phospholipase C zeta 1; testis-development related NYD-SP27; phosphoinositide phospholipase C-zeta-1
 UniProt Protein Name    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
 UniProt Synonym Protein Names   
Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1; Testis-development protein NYD-SP27
 UniProt Gene Name    PLCZ1 [Similar Products]
 UniProt Synonym Gene Names    PLC-zeta-1 [Similar Products]
 UniProt Entry Name    PLCZ1_HUMAN
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 NCBI Summary for PLCzeta1    The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
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 UniProt Comments for PLCzeta1    PLCZ1: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)- dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg- activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Phospholipase; Carbohydrate Metabolism - inositol phosphate; EC 3.1.4.11

Chromosomal Location of Human Ortholog: 12p12.3

Cellular Component: perinuclear region of cytoplasm; cytosol; nucleus

Molecular Function: signal transducer activity; calcium ion binding; phosphoinositide phospholipase C activity

Biological Process: inositol phosphate metabolic process; calcium ion transport; multicellular organismal development; egg activation; lipid catabolic process
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 Research Articles on PLCzeta1    1. Male infertility is associated with the aberrant expression, localisation, structure and function of PLCzeta in human sperm. [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PLCzeta1 elisa kitPathways associated with PLCzeta1 elisa kit
 Reference Product  PubMed Publications
 ITPR1 elisa kit  >2 publications with PLCzeta1 and ITPR1
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway antibodies  D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway Diagram
 D-myo-inositol-5-phosphate Metabolism Pathway antibodies  D-myo-inositol-5-phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism Pathway antibodies  Inositol Phosphate Metabolism Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway antibodies  Inositol Phosphate Metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Organs/Tissues associated with PLCzeta1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >7 publications with PLCzeta1 and Testis
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