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PKR2 elisa kit :: Bovine Prokineticin Receptor 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS013307 PKR2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Prokineticin Receptor 2 (PKR2), ELISA Kit

 Also Known As   

Bovine Prokineticin Receptor 2 ELISA Kit

 Product Gene Name   

PKR2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 20; NC_000020.10 (5282686..5295015, complement). Location: 20p12.3
 OMIM    244200
 3D Structure    ModBase 3D Structure for Q8NFJ6
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 Species Reactivity    Bovine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PKR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PKR2 purchase    MBS013307 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prokineticin Receptor 2 (PKR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PKR2. The ELISA analytical biochemical technique of the MBS013307 kit is based on PKR2 antibody-PKR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PKR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PKR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PKR2. It may not necessarily be applicable to this product.
 NCBI GI #    21426829
 NCBI GeneID    128674
 NCBI Accession #    NP_658986.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_144773.2 [Other Products]
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 UniProt Primary Accession #    Q8NFJ6 [Other Products]
 UniProt Secondary Accession #    Q2M3C0; Q5TDY1; Q9NTT0; A5JUU1 [Other Products]
 UniProt Related Accession #    Q8NFJ6 [Other Products]
 Molecular Weight    43,996 Da
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 NCBI Official Full Name    prokineticin receptor 2
 NCBI Official Synonym Full Names    prokineticin receptor 2
 NCBI Official Symbol    PROKR2 [Similar Products]
 NCBI Official Synonym Symbols   
HH3; KAL3; PKR2; GPRg2; GPR73b; GPR73L1; dJ680N4.3
[Similar Products]
 NCBI Protein Information    prokineticin receptor 2; PK-R2; G protein-coupled receptor 73-like 1
 UniProt Protein Name    Prokineticin receptor 2
 UniProt Synonym Protein Names   
G-protein coupled receptor 73-like 1; GPR73b; GPRg2
 Protein Family    Prokineticin receptor
 UniProt Gene Name    PROKR2 [Similar Products]
 UniProt Synonym Gene Names    GPR73L1; PKR2; PK-R2 [Similar Products]
 UniProt Entry Name    PKR2_HUMAN
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 NCBI Summary for PKR2    Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PKR2    PROKR2: Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. Defects in PROKR2 are the cause of Kallmann syndrome type 3 (KAL3); also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin- releasing hormone-synthesizing neurons. KAL3 patients have variable degrees of olfactory and reproductive dysfunction, but do not show any of the occasional clinical anomalies reported in Kallmann syndrome such as renal agenesis, cleft lip and/or palate, selective tooth agenesis, and bimanual synkinesis. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 20p12.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: neuropeptide Y receptor activity

Biological Process: circadian rhythm; neuropeptide signaling pathway

Disease: Hypogonadotropic Hypogonadism 3 With Or Without Anosmia
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 Research Articles on PKR2    1. The role of PROKR2 in the etiology of congenital hypopituitarism, septo-optic dysplasia, and Kallmann syndrome is uncertain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PKR2 elisa kitPathways associated with PKR2 elisa kit
 Reference Product  PubMed Publications
 PROK2 elisa kit  >76 publications with PKR2 and PROK2
 GNRHR elisa kit  >18 publications with PKR2 and GNRHR
 KISS1R elisa kit  >14 publications with PKR2 and KISS1R
 TAC3 elisa kit  >13 publications with PKR2 and TAC3
 PROK1 elisa kit  >13 publications with PKR2 and PROK1
 TACR3 elisa kit  >12 publications with PKR2 and TACR3
 GNRH1 elisa kit  >8 publications with PKR2 and GNRH1
 KISS1 elisa kit  >4 publications with PKR2 and KISS1
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with PKR2 elisa kitOrgans/Tissues associated with PKR2 elisa kit
 Disease Name  Pubmed Publications
 Kallmann Syndrome Antibodies  >48 publications with PKR2 and Kallmann Syndrome
 Nervous System Diseases Antibodies  >17 publications with PKR2 and Nervous System Diseases
 Brain Diseases Antibodies  >4 publications with PKR2 and Brain Diseases
 Hypertension Antibodies  >2 publications with PKR2 and Hypertension
 Cardiomegaly Antibodies  >1 publications with PKR2 and Cardiomegaly
 Craniofacial Abnormalities Antibodies  >1 publications with PKR2 and Craniofacial Abnormalities
 Fetal Growth Retardation Antibodies  >1 publications with PKR2 and Fetal Growth Retardation
 Nerve Degeneration Antibodies  >1 publications with PKR2 and Nerve Degeneration
 Movement Disorders Antibodies  >1 publications with PKR2 and Movement Disorders
 Weight Loss Antibodies  >1 publications with PKR2 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >19 publications with PKR2 and Brain
 Muscle Antibodies  >5 publications with PKR2 and Muscle
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