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SP-C elisa kit :: Bovine Pulmonary surfatcant-associated protein C, SP-C ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9305205 SP-C elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
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 Product Name   

Pulmonary surfatcant-associated protein C, SP-C, ELISA Kit

★Popular Item★
 Also Known As   

Bovine Pulmonary surfatcant-associated protein C, SP-C ELISA Kit

 Product Gene Name   

SP-C elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 8; NC_000008.10 (22019184..22021992). Location: 8p21
 OMIM    178620
 3D Structure    ModBase 3D Structure for P11686
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 Species Reactivity    Bovine
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    3.12 pg/ml - 100 pg/ml
 Sensitivity    1.0 pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SP-C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SP-C purchase    MBS9305205 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pulmonary surfatcant-associated protein C, SP-C, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12 pg/ml - 100 pg/ml in biological research samples containing SP-C, with an estimated sensitivity of 1.0 pg/ml. The ELISA analytical biochemical technique of the MBS9305205 kit is based on SP-C antibody-SP-C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SP-C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SP-C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SP-C elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPC (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9305205. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SP-C. It may not necessarily be applicable to this product.
 NCBI GI #    288915543
 NCBI GeneID    6440
 NCBI Accession #    NP_001165828.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001172357.1 [Other Products]
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 UniProt Primary Accession #    P11686 [Other Products]
 UniProt Secondary Accession #    P11687; Q12793; Q7Z5D0; A6XNE4; B2RE00; E9PGX3 [Other Products]
 UniProt Related Accession #    P11686 [Other Products]
 Molecular Weight    21,053 Da
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 NCBI Official Full Name    pulmonary surfactant-associated protein C isoform 2 proprotein
 NCBI Official Synonym Full Names    surfactant protein C
 NCBI Official Symbol    SFTPC [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    pulmonary surfactant-associated protein C; SP5; BRICHOS domain containing 6; pulmonary surfactant apoprotein-2 SP-C; pulmonary surfactant-associated proteolipid SPL(Val)
 UniProt Protein Name    Pulmonary surfactant-associated protein C
 UniProt Synonym Protein Names   
Pulmonary surfactant-associated proteolipid SPL(Val); SP5
 UniProt Gene Name    SFTPC [Similar Products]
 UniProt Synonym Gene Names    SFTP2; SP-C [Similar Products]
 UniProt Entry Name    PSPC_HUMAN
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 NCBI Summary for SP-C    This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
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 UniProt Comments for SP-C    SFTPC: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2); also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS); also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: multivesicular body; extracellular space

Molecular Function: protein binding; protein homodimerization activity

Biological Process: circadian rhythm; response to cAMP; response to hyperoxia; response to retinoic acid; response to glucocorticoid stimulus; response to glucose stimulus; response to lipopolysaccharide; respiratory gaseous exchange; protein homooligomerization; response to vitamin A

Disease: Pulmonary Fibrosis, Idiopathic; Surfactant Metabolism Dysfunction, Pulmonary, 2
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 Research Articles on SP-C    1. The A116D mutation leads to impaired processing of proSP-C in alveolar epithelial cells, alters cell viability and lipid composition, and also activates cells of the immune system.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SP-C elisa kitDiseases associated with SP-C elisa kit
 Reference Product  PubMed Publications
 SFTPB elisa kit  >24 publications with SP-C and SFTPB
 SCGB1A1 elisa kit  >15 publications with SP-C and SCGB1A1
 NKX2-1 elisa kit  >7 publications with SP-C and NKX2-1
 SFTPD elisa kit  >4 publications with SP-C and SFTPD
 SFTPA1 elisa kit  >4 publications with SP-C and SFTPA1
 FOXP2 elisa kit  >1 publications with SP-C and FOXP2
 ETV5 elisa kit  >1 publications with SP-C and ETV5
 DNAJC10 elisa kit  >1 publications with SP-C and DNAJC10
 FGF7 elisa kit  >1 publications with SP-C and FGF7
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >106 publications with SP-C and Lung Diseases
 Fibrosis Antibodies  >39 publications with SP-C and Fibrosis
 Idiopathic Pulmonary Fibrosis Antibodies  >23 publications with SP-C and Idiopathic Pulmonary Fibrosis
 Inflammation Antibodies  >21 publications with SP-C and Inflammation
 Neoplasms Antibodies  >13 publications with SP-C and Neoplasms
 Lung Neoplasms Antibodies  >12 publications with SP-C and Lung Neoplasms
 Hyperplasia Antibodies  >12 publications with SP-C and Hyperplasia
 Acute Lung Injury Antibodies  >7 publications with SP-C and Acute Lung Injury
 Necrosis Antibodies  >5 publications with SP-C and Necrosis
 Drug Toxicity Antibodies  >4 publications with SP-C and Drug Toxicity
Organs/Tissues associated with SP-C elisa kit
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >203 publications with SP-C and Lung
 Heart Antibodies  >7 publications with SP-C and Heart
 Kidney Antibodies  >6 publications with SP-C and Kidney
 Brain Antibodies  >6 publications with SP-C and Brain
 Intestine Antibodies  >3 publications with SP-C and Intestine
 Connective Tissue Antibodies  >3 publications with SP-C and Connective Tissue
 Ovary Antibodies  >2 publications with SP-C and Ovary
 Nerve Antibodies  >2 publications with SP-C and Nerve
 Eye Antibodies  >1 publications with SP-C and Eye
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