NP_001243766.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,203 Da
NCBI Official Full Name
queuine tRNA-ribosyltransferase subunit QTRTD1 isoform 4
NCBI Official Synonym Full Names
queuine tRNA-ribosyltransferase domain containing 1
NCBI Protein Information
queuine tRNA-ribosyltransferase subunit QTRTD1; queuine tRNA-ribosyltransferase domain-containing protein 1
UniProt Protein Name
Queuine tRNA-ribosyltransferase subunit QTRTD1
UniProt Synonym Protein Names
Queuine tRNA-ribosyltransferase domain-containing protein 1
UniProt Entry Name
QTRD1_HUMAN
NCBI Summary for QTRTD1
This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for QTRTD1
QTRTD1: Interacts with QTRT1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily.
Protein type: EC 2.4.2.29
Chromosomal Location of Human Ortholog: 3q13.31
Cellular Component: mitochondrion; cytoplasm
Molecular Function: zinc ion binding; queuine tRNA-ribosyltransferase activity
Biological Process: queuosine biosynthetic process
Research Articles on QTRTD1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with QTRTD1 elisa kit
|