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RAP1A elisa kit :: Bovine Ras-Related Protein Rap-1A (RAP1A) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9345303 RAP1A elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ras-Related Protein Rap-1A (RAP1A), ELISA Kit

 Also Known As   

Bovine Ras-Related Protein Rap-1A (RAP1A) ELISA Kit

 Product Gene Name   

RAP1A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    179520
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RAP1A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RAP1A purchase    MBS9345303 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ras-Related Protein Rap-1A (RAP1A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RAP1A. The ELISA analytical biochemical technique of the MBS9345303 kit is based on RAP1A antibody-RAP1A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RAP1A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RAP1A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RAP1A. It may not necessarily be applicable to this product.
 NCBI GI #    4506413
 NCBI GeneID    5906
 NCBI Accession #    NP_002875.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002884.3 [Other Products]
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 UniProt Secondary Accession #    P10113 [Other Products]
 UniProt Related Accession #    P62834 [Other Products]
 Molecular Weight    20,987 Da
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 NCBI Official Full Name    ras-related protein Rap-1A
 NCBI Official Synonym Full Names    RAP1A, member of RAS oncogene family
 NCBI Official Symbol    RAP1A [Similar Products]
 NCBI Official Synonym Symbols   
RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21
[Similar Products]
 NCBI Protein Information    ras-related protein Rap-1A
 UniProt Protein Name    Ras-related protein Rap-1A
 UniProt Synonym Protein Names   
C21KG; G-22K; GTP-binding protein smg p21A; Ras-related protein Krev-1
 Protein Family    Ras-related protein
 UniProt Gene Name    RAP1A [Similar Products]
 UniProt Synonym Gene Names    KREV1 [Similar Products]
 UniProt Entry Name    RAP1A_HUMAN
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 NCBI Summary for RAP1A    This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
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 UniProt Comments for RAP1A    RAP1A: a small G protein of the Ras family with tumor suppressor activity. Induces morphological reversion of a cell line transformed by a Ras oncogene. Activated by guanine nucleotide-exchange factors (GEF) EPAC and EPAC2 in a cAMP-dependent manner, and GFR. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Interacts with SGSM1, SGSM2 and SGSM3.

Protein type: G protein, monomeric; Motility/polarity/chemotaxis; G protein, monomeric, Ras; Tumor suppressor; G protein

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: cell junction; cytoplasm; cytosol; early endosome; late endosome; myelin sheath; neuron projection; perinuclear region of cytoplasm; plasma membrane

Molecular Function: GTP binding; GTPase activity; protein binding; protein complex binding; protein transporter activity; Rap guanyl-nucleotide exchange factor activity; Ras GTPase binding

Biological Process: activation of MAPKK activity; blood coagulation; energy reserve metabolic process; microvillus biogenesis; negative regulation of collagen biosynthetic process; nerve growth factor receptor signaling pathway; platelet activation; positive regulation of glucose import; positive regulation of GTPase activity; positive regulation of phagocytosis; positive regulation of protein kinase activity; protein transport; Rap protein signal transduction; regulation of insulin secretion; signal transduction
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 Research Articles on RAP1A    1. These findings provide further evidence that a crucial role for miR-203 in inhibiting metastasis of PCa through the suppression of Rap1A expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RAP1A elisa kitPathways associated with RAP1A elisa kit
 Reference Product  PubMed Publications
 RALGDS elisa kit  >13 publications with RAP1A and RALGDS
 RAF1 elisa kit  >5 publications with RAP1A and RAF1
 RAPGEF2 elisa kit  >3 publications with RAP1A and RAPGEF2
 BRAF elisa kit  >2 publications with RAP1A and BRAF
 APBB1IP elisa kit  >2 publications with RAP1A and APBB1IP
 AKT1 elisa kit  >2 publications with RAP1A and AKT1
 RASGRP2 elisa kit  >1 publications with RAP1A and RASGRP2
 MLLT4 elisa kit  >1 publications with RAP1A and MLLT4
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class I PI3K Signaling Events Pathway antibodies  Class I PI3K Signaling Events Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
Diseases associated with RAP1A elisa kitOrgans/Tissues associated with RAP1A elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >15 publications with RAP1A and Cardiovascular Diseases
 Respiratory Tract Diseases Antibodies  >13 publications with RAP1A and Respiratory Tract Diseases
 Breast Neoplasms Antibodies  >12 publications with RAP1A and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >12 publications with RAP1A and Cell Transformation, Neoplastic
 Lung Neoplasms Antibodies  >12 publications with RAP1A and Lung Neoplasms
 Lung Diseases Antibodies  >12 publications with RAP1A and Lung Diseases
 Vascular Diseases Antibodies  >11 publications with RAP1A and Vascular Diseases
 Inflammation Antibodies  >10 publications with RAP1A and Inflammation
 Neoplasm Metastasis Antibodies  >7 publications with RAP1A and Neoplasm Metastasis
 Necrosis Antibodies  >7 publications with RAP1A and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >75 publications with RAP1A and Blood
 Bone Antibodies  >39 publications with RAP1A and Bone
 Vascular Antibodies  >34 publications with RAP1A and Vascular
 Muscle Antibodies  >27 publications with RAP1A and Muscle
 Brain Antibodies  >22 publications with RAP1A and Brain
 Lung Antibodies  >21 publications with RAP1A and Lung
 Kidney Antibodies  >11 publications with RAP1A and Kidney
 Nerve Antibodies  >10 publications with RAP1A and Nerve
 Heart Antibodies  >10 publications with RAP1A and Heart
 Prostate Antibodies  >10 publications with RAP1A and Prostate
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