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ARHGDIA elisa kit :: Bovine Rho Gdp Dissociation Inhibitor Alpha ELISA Kit

Scan QR to view Datasheet Catalog #    MBS038550 ARHGDIA elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Rho Gdp Dissociation Inhibitor Alpha (ARHGDIA), ELISA Kit

 Also Known As   

Bovine Rho Gdp Dissociation Inhibitor Alpha ELISA Kit

 Product Gene Name   

ARHGDIA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 17; NC_000017.10 (79825597..79829282, complement). Location: 17q25.3
 OMIM    601925
 3D Structure    ModBase 3D Structure for P52565
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 Species Reactivity    Bovine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ARHGDIA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ARHGDIA purchase    MBS038550 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Rho Gdp Dissociation Inhibitor Alpha (ARHGDIA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ARHGDIA. The ELISA analytical biochemical technique of the MBS038550 kit is based on ARHGDIA antibody-ARHGDIA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ARHGDIA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ARHGDIA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ARHGDIA. It may not necessarily be applicable to this product.
 NCBI GI #    48145671
 NCBI GeneID    396
 NCBI Accession #    CAG33058.1 [Other Products]
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 UniProt Primary Accession #    P52565 [Other Products]
 UniProt Secondary Accession #    Q6IBM5; A8MXW0; B2R5X1; B4DDD3; B4DUV9 [Other Products]
 UniProt Related Accession #    P52565 [Other Products]
 Molecular Weight    23,207 Da
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 NCBI Official Full Name    ARHGDIA
 NCBI Official Synonym Full Names    Rho GDP dissociation inhibitor (GDI) alpha
 NCBI Official Symbol    ARHGDIA [Similar Products]
 NCBI Official Synonym Symbols   
GDIA1; NPHS8; RHOGDI; RHOGDI-1
[Similar Products]
 NCBI Protein Information    rho GDP-dissociation inhibitor 1; rho GDI 1; rho-GDI alpha
 UniProt Protein Name    Rho GDP-dissociation inhibitor 1
 UniProt Synonym Protein Names   
Rho-GDI alpha
 UniProt Gene Name    ARHGDIA [Similar Products]
 UniProt Synonym Gene Names    GDIA1; Rho GDI 1 [Similar Products]
 UniProt Entry Name    GDIR1_HUMAN
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 NCBI Summary for ARHGDIA    Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA (Leffers et al., 1993 [PubMed 8262133]).[supplied by OMIM, Jan 2009]
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 UniProt Comments for ARHGDIA    RhoGDI alpha: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Monomer. Forms a heterodimer with RAC1. Interacts with FER. Belongs to the Rho GDI family.

Protein type: Motility/polarity/chemotaxis; Apoptosis; G protein regulator, misc.; Cell adhesion; Cell development/differentiation

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: cytoskeleton; immunological synapse; cytosol

Molecular Function: protein binding; Rho GDP-dissociation inhibitor activity; GTPase activator activity

Biological Process: nerve growth factor receptor signaling pathway; negative regulation of cell adhesion; regulation of axonogenesis; Rho protein signal transduction; regulation of small GTPase mediated signal transduction; regulation of protein localization; small GTPase mediated signal transduction; negative regulation of axonogenesis; positive regulation of axonogenesis; cell motility; negative regulation of cell migration; negative regulation of apoptosis; positive regulation of GTPase activity

Disease: Nephrotic Syndrome, Type 8
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 Research Articles on ARHGDIA    1. demonstrate that membrane extraction of Rho GTPase by RhoGDI is a thermodynamically favored passive process that operates through a series of progressively tighter intermediates, much like the one that is mediated by RabGDI
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ARHGDIA elisa kitPathways associated with ARHGDIA elisa kit
 Reference Product  PubMed Publications
 RHOA elisa kit  >41 publications with ARHGDIA and RHOA
 RAC1 elisa kit  >30 publications with ARHGDIA and RAC1
 CDC42 elisa kit  >28 publications with ARHGDIA and CDC42
 BCR elisa kit  >3 publications with ARHGDIA and BCR
 RAC2 elisa kit  >2 publications with ARHGDIA and RAC2
 NGFR elisa kit  >1 publications with ARHGDIA and NGFR
 Products by Pathway  Pathway Diagram
 Axonal Growth Inhibition (RHOA Activation) Pathway antibodies  Axonal Growth Inhibition (RHOA Activation) Pathway Diagram
 Axonal Growth Stimulation Pathway antibodies  Axonal Growth Stimulation Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
 RAC1 Signaling Pathway antibodies  RAC1 Signaling Pathway Diagram
 Regulation Of CDC42 Activity Pathway antibodies  Regulation Of CDC42 Activity Pathway Diagram
 Regulation Of RAC1 Activity Pathway antibodies  Regulation Of RAC1 Activity Pathway Diagram
 Regulation Of RhoA Activity Pathway antibodies  Regulation Of RhoA Activity Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
Diseases associated with ARHGDIA elisa kitOrgans/Tissues associated with ARHGDIA elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >33 publications with ARHGDIA and Neoplasms
 Neoplasm Metastasis Antibodies  >8 publications with ARHGDIA and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >5 publications with ARHGDIA and Adenocarcinoma
 Brain Diseases Antibodies  >4 publications with ARHGDIA and Brain Diseases
 Cardiovascular Diseases Antibodies  >4 publications with ARHGDIA and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >4 publications with ARHGDIA and Nervous System Diseases
 Breast Neoplasms Antibodies  >4 publications with ARHGDIA and Breast Neoplasms
 Lung Diseases Antibodies  >3 publications with ARHGDIA and Lung Diseases
 Proteinuria Antibodies  >3 publications with ARHGDIA and Proteinuria
 Kidney Diseases Antibodies  >2 publications with ARHGDIA and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with ARHGDIA and Brain
 Muscle Antibodies  >7 publications with ARHGDIA and Muscle
 Blood Antibodies  >6 publications with ARHGDIA and Blood
 Kidney Antibodies  >5 publications with ARHGDIA and Kidney
 Lung Antibodies  >4 publications with ARHGDIA and Lung
 Bone Marrow Antibodies  >3 publications with ARHGDIA and Bone Marrow
 Vascular Antibodies  >3 publications with ARHGDIA and Vascular
 Heart Antibodies  >3 publications with ARHGDIA and Heart
 Bone Antibodies  >3 publications with ARHGDIA and Bone
 Eye Antibodies  >2 publications with ARHGDIA and Eye
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