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SUPT5H elisa kit :: Bovine Transcription elongation factor SPT5 (SUPT5H) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7245674 SUPT5H elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Transcription elongation factor SPT5 (SUPT5H), ELISA Kit

 Also Known As   

Bovine Transcription elongation factor SPT5 (SUPT5H) ELISA Kit

 Product Gene Name   

SUPT5H elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    602102
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SUPT5H elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SUPT5H purchase    MBS7245674 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transcription elongation factor SPT5 (SUPT5H) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SUPT5H. The ELISA analytical biochemical technique of the MBS7245674 kit is based on SUPT5H antibody-SUPT5H antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SUPT5H antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SUPT5H. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for SUPT5H elisa kit    Cancer
NCBI/Uniprot data below describe general gene information for SUPT5H. It may not necessarily be applicable to this product.
 NCBI GI #    20149524
 NCBI GeneID    6829
 NCBI Accession #    NP_003160.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003169.3 [Other Products]
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 UniProt Secondary Accession #    O43279; Q59G52; Q99639 [Other Products]
 UniProt Related Accession #    O00267 [Other Products]
 Molecular Weight    120,499 Da
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 NCBI Official Full Name    transcription elongation factor SPT5 isoform a
 NCBI Official Synonym Full Names    suppressor of Ty 5 homolog (S. cerevisiae)
 NCBI Official Symbol    SUPT5H [Similar Products]
 NCBI Official Synonym Symbols   
SPT5; SPT5H; Tat-CT1
[Similar Products]
 NCBI Protein Information    transcription elongation factor SPT5; hSPT5; DSIF p160; DSIF large subunit; Tat-cotransactivator 1 protein; DRB sensitivity-inducing factor large subunit; DRB sensitivity-inducing factor 160 kDa subunit
 UniProt Protein Name    Transcription elongation factor SPT5
 UniProt Synonym Protein Names   
DRB sensitivity-inducing factor 160 kDa subunit; DSIF p160; DRB sensitivity-inducing factor large subunit; DSIF large subunit; Tat-cotransactivator 1 protein; Tat-CT1 protein
 UniProt Gene Name    SUPT5H [Similar Products]
 UniProt Synonym Gene Names    SPT5; SPT5H; hSPT5; DSIF p160; DSIF large subunit; Tat-CT1 protein [Similar Products]
 UniProt Entry Name    SPT5H_HUMAN
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 UniProt Comments for SUPT5H    SPT5: a transcription elongation factor. Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Two alternatively spliced human isoforms have been described.

Protein type: RNA-binding; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; enzyme binding; protein heterodimerization activity; chromatin binding

Biological Process: transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; positive regulation of RNA elongation; negative regulation of RNA elongation; negative regulation of transcription from RNA polymerase II promoter; cell cycle; response to organic substance; chromatin remodeling; mRNA capping; RNA elongation; RNA elongation from RNA polymerase II promoter; gene expression; positive regulation of transcription from RNA polymerase II promoter; positive regulation of macroautophagy
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 Research Articles on SUPT5H    1. Data indicate that the Plus3 domain of the Rtf1 subunit mediates Paf1C recruitment to genes by binding a repeating domain within the phosphorylated elongation factor Spt5.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SUPT5H elisa kitPathways associated with SUPT5H elisa kit
 Reference Product  PubMed Publications
 SUPT4H1 elisa kit  >5 publications with SUPT5H and SUPT4H1
 CDK9 elisa kit  >3 publications with SUPT5H and CDK9
 PAF1 elisa kit  >2 publications with SUPT5H and PAF1
 SUPT6H elisa kit  >2 publications with SUPT5H and SUPT6H
 RTF1 elisa kit  >1 publications with SUPT5H and RTF1
 Products by Pathway  Pathway Diagram
 Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway antibodies  Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway antibodies  Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway Diagram
 Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies  Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
 Formation Of RNA Pol II Elongation Complex Pathway antibodies  Formation Of RNA Pol II Elongation Complex Pathway Diagram
 Formation Of The Early Elongation Complex Pathway antibodies  Formation Of The Early Elongation Complex Pathway Diagram
 Formation Of The HIV-1 Early Elongation Complex Pathway antibodies  Formation Of The HIV-1 Early Elongation Complex Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
Diseases associated with SUPT5H elisa kitOrgans/Tissues associated with SUPT5H elisa kit
 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >1 publications with SUPT5H and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with SUPT5H and Blood
 Brain Antibodies  >2 publications with SUPT5H and Brain
 Heart Antibodies  >1 publications with SUPT5H and Heart
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