CAG46756.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,907 Da
NCBI Official Full Name
TUBB
NCBI Official Synonym Full Names
tubulin, beta 2A class IIa
NCBI Protein Information
tubulin beta-2A chain; class IIa beta-tubulin; tubulin beta class IIa; tubulin, beta polypeptide 2
UniProt Protein Name
Tubulin beta-2A chain
UniProt Synonym Protein Names
Tubulin beta class IIa
UniProt Synonym Gene Names
UniProt Entry Name
TBB2A_HUMAN
NCBI Summary for TUBB
Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
UniProt Comments for TUBB
TUBB2A: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 6p25
Cellular Component: microtubule; cytoplasm; nucleus; vesicle
Molecular Function: GTPase activity; GTP binding; structural constituent of cytoskeleton
Biological Process: protein polymerization; 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; transmembrane transport; microtubule-based process
Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 5
Research Articles on TUBB
Precautions
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Pathways associated with TUBB elisa kit
Diseases associated with TUBB elisa kit
Organs/Tissues associated with TUBB elisa kit
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