Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow CK-HMW rightarrow Bovine CK-HMW  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • achaete-scute complex homolog 2 (Drosophila) (ASCL2) ELISA Kit
 • Kidney Injury Molecule 1 (KIM1) ELISA Kit
 • UPF0317 protein BAD_0077 (BAD_0077) Recombinant Protein
 • Uncharacterized protein AF_1994 (AF_1994) Recombinant Protein
 • OR52E5 Antibody
 • Protein L, Peptostreptococcus Magnus Recombinant Protein
 • LEC - NCC-4 Antibody
 • Lin-28 Homolog A (LIN28A) ELISA Kit
 • Leptin ELISA Kit
 • Nephrin ELISA Kit
 • Purification Media, Maleimide-OvA, BioSeparation Bead
 • TSH Antibody
 • FXYD domain containing ion transport regulator 1 (FXYD1) Antibody
 • Dehydroepiandrosterone sulfate (DHEA-S) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CK-HMW elisa kit :: Bovine cytokeratin High Molecular Weight (CK-HMW) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2608958 CK-HMW elisa kit
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cytokeratin High Molecular Weight (CK-HMW), ELISA Kit

 Also Known As   

Bovine cytokeratin High Molecular Weight(CK-HMW) ELISA Kit

 Product Gene Name   

CK-HMW elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Manual Insert    Request Manual
 OMIM    L04636 mRNA
Section Bar
 Species Reactivity    Bovine
Section Bar
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of CK-HMW elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CK-HMW purchase    MBS2608958 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cytokeratin High Molecular Weight (CK-HMW) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CK-HMW. The ELISA analytical biochemical technique of the MBS2608958 kit is based on CK-HMW antibody-CK-HMW antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CK-HMW antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CK-HMW. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CK-HMW. It may not necessarily be applicable to this product.
 NCBI GI #    730772
 NCBI GeneID    708
 NCBI Accession #    Q07021.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q2HXR8; Q9NNY8 [Other Products]
 UniProt Related Accession #    Q07021 [Other Products]
 Molecular Weight    31,362 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Complement component 1 Q subcomponent-binding protein, mitochondrial
 NCBI Official Synonym Full Names    complement C1q binding protein
 NCBI Official Symbol    C1QBP [Similar Products]
 NCBI Official Synonym Symbols   
p32; HABP1; gC1qR; GC1QBP; SF2p32; gC1Q-R
[Similar Products]
 NCBI Protein Information    complement component 1 Q subcomponent-binding protein, mitochondrial
 UniProt Protein Name    Complement component 1 Q subcomponent-binding protein, mitochondrial
 UniProt Synonym Protein Names   
ASF/SF2-associated protein p32; Glycoprotein gC1qBP; C1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; gC1q-R protein; p33
 UniProt Gene Name    C1QBP [Similar Products]
 UniProt Synonym Gene Names    GC1QBP; HABP1; SF2P32; C1qBP [Similar Products]
 UniProt Entry Name    C1QBP_HUMAN
Section Bar
 NCBI Summary for CK-HMW    The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for CK-HMW    C1QBP: a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. Originally identified via its binding interactions with Splicing Factor (SF-2). Multiple, diverse binding partners of C1QBP were subsequently identified, including the globular heads of complement component C1q, hyaluronic acid, selected protein kinases, the tumor suppressor ARF, and multiple antigens of bacterial and viral origin. Overexpressed in a number of cancer cell types, and has been implicated in the Warburg effect, whereby cancer cells shift their metabolism from oxidative phosphorylation to glycolysis. Inhibits the Mitochondrial Permeability Transition (MPT) pore, possibly serving a protective function against damage from oxidative stress. Binding to C1q inhibits C1. In complex with cytokeratin-1/KRT1 is a high affinty receptor for kininogen-1/HMWK. The secreted form may enhance both extrinsic and intrinsic coagulation pathways. The cell surface form may require docking with transmembrane proteins for downstream signaling which might be specific for a cell-type or response. Belongs to the MAM33 family.

Protein type: Mitochondrial; Motility/polarity/chemotaxis; Nucleolus; Receptor, misc.

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: cell surface; cytoplasm; cytosol; membrane; mitochondrion; nucleus; plasma membrane

Molecular Function: adrenergic receptor binding; complement component C1q binding; hyaluronic acid binding; kininogen binding; mRNA binding; protein binding; transcription corepressor activity; transcription factor binding

Biological Process: blood coagulation, intrinsic pathway; immune response; mature ribosome assembly; negative regulation of defense response to virus; negative regulation of interferon-gamma production; negative regulation of interleukin-12 production; negative regulation of nuclear mRNA splicing, via spliceosome; negative regulation of transcription from RNA polymerase II promoter; phosphoinositide 3-kinase cascade; positive regulation of apoptosis; positive regulation of cell adhesion; positive regulation of protein kinase B signaling cascade; regulation of complement activation
Table BarTOPTable Bar
 Research Articles on CK-HMW    1. C1QBP interacts with DLAT and regulates the enzyme activity of pyruvate dehydrogenase.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with CK-HMW elisa kitDiseases associated with CK-HMW elisa kit
 Products by Pathway  Pathway Diagram
 Endoderm Differentiation Pathway antibodies  Endoderm Differentiation Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Intrinsic Pathway Of Fibrin Clot Formation antibodies  Intrinsic Pathway Of Fibrin Clot Formation Diagram
 Mesodermal Commitment Pathway antibodies  Mesodermal Commitment Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >41 publications with CK-HMW and Inflammation
 Hepatitis Antibodies  >15 publications with CK-HMW and Hepatitis
 Lung Diseases Antibodies  >11 publications with CK-HMW and Lung Diseases
 Cardiovascular Diseases Antibodies  >8 publications with CK-HMW and Cardiovascular Diseases
 Liver Diseases Antibodies  >8 publications with CK-HMW and Liver Diseases
 Breast Neoplasms Antibodies  >8 publications with CK-HMW and Breast Neoplasms
 Necrosis Antibodies  >7 publications with CK-HMW and Necrosis
 Disease Models, Animal Antibodies  >6 publications with CK-HMW and Disease Models, Animal
 Nervous System Diseases Antibodies  >6 publications with CK-HMW and Nervous System Diseases
 Liver Neoplasms Antibodies  >5 publications with CK-HMW and Liver Neoplasms
Organs/Tissues associated with CK-HMW elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >125 publications with CK-HMW and Blood
 Vascular Antibodies  >48 publications with CK-HMW and Vascular
 Lung Antibodies  >27 publications with CK-HMW and Lung
 Embryonic Tissue Antibodies  >20 publications with CK-HMW and Embryonic Tissue
 Liver Antibodies  >14 publications with CK-HMW and Liver
 Brain Antibodies  >14 publications with CK-HMW and Brain
 Bone Antibodies  >12 publications with CK-HMW and Bone
 Skin Antibodies  >11 publications with CK-HMW and Skin
 Muscle Antibodies  >9 publications with CK-HMW and Muscle
 Bone Marrow Antibodies  >9 publications with CK-HMW and Bone Marrow
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions