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MLYCD elisa kit :: Bovine malonyl coenzyme A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602799 MLYCD elisa kit
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

malonyl coenzyme A (MLYCD), ELISA Kit

 Also Known As   

Bovine malonyl coenzyme A ELISA Kit

 Product Gene Name   

MLYCD elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606761
 3D Structure    ModBase 3D Structure for O95822
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 Species Reactivity    Bovine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MLYCD elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MLYCD purchase    MBS2602799 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the malonyl coenzyme A (MLYCD) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MLYCD. The ELISA analytical biochemical technique of the MBS2602799 kit is based on MLYCD antibody-MLYCD antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MLYCD antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MLYCD. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MLYCD. It may not necessarily be applicable to this product.
 NCBI GI #    110349750
 NCBI GeneID    23417
 NCBI Accession #    NP_036345.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_012213.2 [Other Products]
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 UniProt Primary Accession #    O95822 [Other Products]
 UniProt Secondary Accession #    Q9UNU5; Q9Y3F2 [Other Products]
 UniProt Related Accession #    O95822 [Other Products]
 Molecular Weight    50,946 Da [Similar Products]
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 NCBI Official Full Name    malonyl-CoA decarboxylase, mitochondrial
 NCBI Official Synonym Full Names    malonyl-CoA decarboxylase
 NCBI Official Symbol    MLYCD [Similar Products]
 NCBI Official Synonym Symbols   
MCD
[Similar Products]
 NCBI Protein Information    malonyl-CoA decarboxylase, mitochondrial; malonyl coenzyme A decarboxylase
 UniProt Protein Name    Malonyl-CoA decarboxylase, mitochondrial
 Protein Family    Malonyl-CoA decarboxylase
 UniProt Gene Name    MLYCD [Similar Products]
 UniProt Synonym Gene Names    MCD [Similar Products]
 UniProt Entry Name    DCMC_HUMAN
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 NCBI Summary for MLYCD    The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MLYCD    MLYCD: Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Defects in MLYCD are the cause of malonyl-CoA decarboxylase deficiency (MLYCD deficiency). MLYCD deficiency is an autosomal recessive disease characterized by abdominal pain, chronic constipation, episodic vomiting, metabolic acidosis and malonic aciduria.

Protein type: Lyase; Carbohydrate Metabolism - propanoate; EC 4.1.1.9; Other Amino Acids Metabolism - beta-alanine

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: peroxisomal matrix; mitochondrion; mitochondrial matrix; cytoplasm; peroxisome

Molecular Function: receptor binding; malonyl-CoA decarboxylase activity

Biological Process: positive regulation of fatty acid oxidation; acetyl-CoA biosynthetic process; cellular lipid metabolic process; fatty acid biosynthetic process

Disease: Malonyl-coa Decarboxylase Deficiency
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 Research Articles on MLYCD    1. The MLYCD catalytic domain is structurally homologous to those of the GCN5-related N-acetyltransferase superfamily.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MLYCD elisa kitDiseases associated with MLYCD elisa kit
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Peroxisomal Lipid Metabolism Pathway antibodies  Peroxisomal Lipid Metabolism Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Propanoate Metabolism Pathway antibodies  Propanoate Metabolism Pathway Diagram
 Propanoate Metabolism Pathway antibodies  Propanoate Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Malonic aciduria Antibodies  >7 publications with MLYCD and Malonic aciduria
 Acidosis Antibodies  >3 publications with MLYCD and Acidosis
 Cardiovascular Diseases Antibodies  >3 publications with MLYCD and Cardiovascular Diseases
 Congenital Abnormalities Antibodies  >2 publications with MLYCD and Congenital Abnormalities
 Weight Gain Antibodies  >2 publications with MLYCD and Weight Gain
 Insulin Resistance Antibodies  >1 publications with MLYCD and Insulin Resistance
 Disease Models, Animal Antibodies  >1 publications with MLYCD and Disease Models, Animal
 Liver Diseases Antibodies  >1 publications with MLYCD and Liver Diseases
 Fatty Liver Antibodies  >1 publications with MLYCD and Fatty Liver
 Drug-Induced Liver Injury Antibodies  >1 publications with MLYCD and Drug-Induced Liver Injury
Organs/Tissues associated with MLYCD elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with MLYCD and Brain
 Heart Antibodies  >2 publications with MLYCD and Heart
 Blood Antibodies  >1 publications with MLYCD and Blood
 Skin Antibodies  >1 publications with MLYCD and Skin
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