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SCD163 elisa kit :: Bovine sCD163/Soluble Haemoglobin Scavenger Receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS044938 SCD163 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

sCD163/Soluble Haemoglobin Scavenger Receptor, ELISA Kit

★Popular Item★
 Also Known As   

Bovine sCD163/Soluble Haemoglobin Scavenger Receptor ELISA Kit

 Product Gene Name   

SCD163 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    605545
 3D Structure    ModBase 3D Structure for Q86VB7
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 Species Reactivity    Bovine
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    62.5 ng/ml - 2000 ng/ml
 Sensitivity    10 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SCD163 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SCD163 purchase    MBS044938 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the sCD163/Soluble Haemoglobin Scavenger Receptor, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 ng/ml - 2000 ng/ml in biological research samples containing SCD163, with an estimated sensitivity of 10 ng/ml. The ELISA analytical biochemical technique of the MBS044938 kit is based on SCD163 antibody-SCD163 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SCD163 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SCD163. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for SCD163 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SCD163 (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS044938. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SCD163. It may not necessarily be applicable to this product.
 NCBI GI #    344179110
 NCBI GeneID    9332
 NCBI Accession #    NP_004235.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_004244.5 [Other Products]
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 UniProt Primary Accession #    Q86VB7 [Other Products]
 UniProt Secondary Accession #    Q07898; Q07899; Q07900; Q07901; Q2VLH7; C9JIG2 [Other Products]
 UniProt Related Accession #    Q86VB7 [Other Products]
 Molecular Weight    125,451 Da
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 NCBI Official Full Name    scavenger receptor cysteine-rich type 1 protein M130 isoform a
 NCBI Official Synonym Full Names    CD163 molecule
 NCBI Official Symbol    CD163 [Similar Products]
 NCBI Official Synonym Symbols   
M130; MM130
[Similar Products]
 NCBI Protein Information    scavenger receptor cysteine-rich type 1 protein M130; hemoglobin scavenger receptor; macrophage-associated antigen
 UniProt Protein Name    Scavenger receptor cysteine-rich type 1 protein M130
 UniProt Synonym Protein Names   
Hemoglobin scavenger receptor
 UniProt Gene Name    CD163 [Similar Products]
 UniProt Synonym Gene Names    M130; sCD163 [Similar Products]
 UniProt Entry Name    C163A_HUMAN
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 NCBI Summary for SCD163    The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
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 UniProt Comments for SCD163    CD163: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: integral to plasma membrane; extracellular region; plasma membrane

Molecular Function: protein binding; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; acute-phase response
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 Research Articles on SCD163    1. sCD163 correlates with CD163 mRNA expression in subcutaneous and visceral adipose tissue and with whole-body insulin sensitivity in the steady-state condition.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SCD163 elisa kitPathways associated with SCD163 elisa kit
 Reference Product  PubMed Publications
 CD68 elisa kit  >364 publications with SCD163 and CD68
 IL10 elisa kit  >92 publications with SCD163 and IL10
 HMOX1 elisa kit  >42 publications with SCD163 and HMOX1
 CSF1R elisa kit  >28 publications with SCD163 and CSF1R
 IL6 elisa kit  >11 publications with SCD163 and IL6
 C1QB elisa kit  >1 publications with SCD163 and C1QB
 VSIG4 elisa kit  >1 publications with SCD163 and VSIG4
 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
Diseases associated with SCD163 elisa kitOrgans/Tissues associated with SCD163 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >354 publications with SCD163 and Inflammation
 Neoplasms Antibodies  >254 publications with SCD163 and Neoplasms
 Necrosis Antibodies  >157 publications with SCD163 and Necrosis
 Nervous System Diseases Antibodies  >102 publications with SCD163 and Nervous System Diseases
 Brain Diseases Antibodies  >63 publications with SCD163 and Brain Diseases
 Fibrosis Antibodies  >55 publications with SCD163 and Fibrosis
 Lung Diseases Antibodies  >46 publications with SCD163 and Lung Diseases
 Adenocarcinoma Antibodies  >39 publications with SCD163 and Adenocarcinoma
 Heart Diseases Antibodies  >29 publications with SCD163 and Heart Diseases
 Kidney Diseases Antibodies  >27 publications with SCD163 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >592 publications with SCD163 and Blood
 Vascular Antibodies  >167 publications with SCD163 and Vascular
 Skin Antibodies  >108 publications with SCD163 and Skin
 Bone Antibodies  >100 publications with SCD163 and Bone
 Liver Antibodies  >99 publications with SCD163 and Liver
 Brain Antibodies  >70 publications with SCD163 and Brain
 Lung Antibodies  >68 publications with SCD163 and Lung
 Connective Tissue Antibodies  >46 publications with SCD163 and Connective Tissue
 Heart Antibodies  >40 publications with SCD163 and Heart
 Spleen Antibodies  >39 publications with SCD163 and Spleen
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