NP_001073697.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
47,984 Da
NCBI Official Full Name
transcription factor AP-2-alpha
NCBI Official Synonym Full Names
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)<
NCBI Protein Information
transcription factor AP-2-alpha; AP2-alpha; activator protein 2; AP-2 transcription factor; activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha
UniProt Protein Name
Transcription factor AP-2-alpha
UniProt Synonym Protein Names
AP-2 transcription factor; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2
UniProt Synonym Gene Names
UniProt Entry Name
AP2A_BOVIN
UniProt Comments for TFAP2A
Function: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region
Research Articles on TFAP2A
Precautions
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Disclaimer
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Diseases associated with TFAP2A elisa kit
Organs/Tissues associated with TFAP2A elisa kit
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