NP_001757.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,717 Da
NCBI Official Full Name
antigen-presenting glycoprotein CD1d isoform 1
NCBI Official Synonym Full Names
CD1d molecule
NCBI Protein Information
antigen-presenting glycoprotein CD1d
UniProt Protein Name
Antigen-presenting glycoprotein CD1d
UniProt Synonym Protein Names
R3G1; CD_antigen: CD1d
NCBI Summary for CD1D
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
UniProt Comments for CD1D
CD1D: Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
Protein type: Apoptosis; Cell surface; Lipid-binding; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: basolateral plasma membrane; cell surface; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; endosome membrane; integral component of plasma membrane; lysosomal membrane; plasma membrane
Molecular Function: beta-2-microglobulin binding; cell adhesion molecule binding; endogenous lipid antigen binding; exogenous lipid antigen binding; histone binding; lipid antigen binding; receptor activity
Biological Process: antigen processing and presentation, endogenous lipid antigen via MHC class Ib; antigen processing and presentation, exogenous lipid antigen via MHC class Ib; detection of bacterium; heterotypic cell-cell adhesion; innate immune response; positive regulation of innate immune response; positive regulation of T cell proliferation; regulation of immune response; T cell selection; viral process
Research Articles on CD1D
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with CD1D elisa kit
Pathways associated with CD1D elisa kit
Diseases associated with CD1D elisa kit
Organs/Tissues associated with CD1D elisa kit
|