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BECLIN 1 elisa kit :: Camel Beclin 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS059668 BECLIN 1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Beclin 1, ELISA Kit

★Popular Item★
 Also Known As   

Camel Beclin 1 ELISA Kit

 Product Gene Name   

BECLIN 1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 17; NC_000017.10 (40962150..40976310, complement). Location: 17q21
 OMIM    604378
 3D Structure    ModBase 3D Structure for Q14457
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 Species Reactivity    Camel
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BECLIN 1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BECLIN 1 purchase    MBS059668 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Beclin 1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing BECLIN 1. The ELISA analytical biochemical technique of the MBS059668 kit is based on BECLIN 1 antibody-BECLIN 1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BECLIN 1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BECLIN 1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Sample Manual Insert of MBS059668. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BECLIN 1. It may not necessarily be applicable to this product.
 NCBI GI #    4680381
 NCBI GeneID    8678
 NCBI Accession #    AAD27650.1 [Other Products]
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 UniProt Primary Accession #    Q14457 [Other Products]
 UniProt Secondary Accession #    O75595; Q9UNA8 [Other Products]
 UniProt Related Accession #    Q14457 [Other Products]
 Molecular Weight    51,896 Da
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 NCBI Official Full Name    beclin 1
 NCBI Official Synonym Full Names    beclin 1, autophagy related
 NCBI Official Symbol    BECN1 [Similar Products]
 NCBI Official Synonym Symbols   
ATG6; VPS30; beclin1
[Similar Products]
 NCBI Protein Information    beclin-1; ATG6 autophagy related 6 homolog; coiled-coil myosin-like BCL2-interacting protein; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)
 UniProt Protein Name    Beclin-1
 UniProt Synonym Protein Names   
Coiled-coil myosin-like BCL2-interacting protein; Protein GT197
 Protein Family    Beclin 1-associated autophagy-related key regulator
 UniProt Gene Name    BECN1 [Similar Products]
 UniProt Synonym Gene Names    GT197 [Similar Products]
 UniProt Entry Name    BECN1_HUMAN
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 NCBI Summary for BECLIN 1    Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM, Jul 2010]
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 UniProt Comments for BECLIN 1    beclin 1: an essential autophagy protein that has been linked to multiple processes including tumor suppression, protection against some cardiac and neurological degenerative diseases, and lifespan extension. A ubiquitous protein of the beclin family. Is part of the class III PI3K complex that induces autophagy. Expressed at elevated levels in dendrites and cell bodies of cerebellar Purkinje cells. Interacts with the anti-apoptotic protein Bcl-2, which inhibits autophagy when it is present in the endoplasmic reticulum. The dissociation of ATG6 from Bcl-2 is essential for its autophagic activity. Interacts with PITC and GluR-delta2. Probably forms a complex with AMBRA1 and PIK3C3. Plays a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Protein type: Membrane protein, peripheral; Adaptor/scaffold; Autophagy

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: extrinsic to membrane; mitochondrion; endoplasmic reticulum; cytoplasmic membrane-bound vesicle; dendrite; trans-Golgi network; phagocytic vesicle; nucleus; endosome

Molecular Function: protein binding; phosphoinositide 3-kinase binding

Biological Process: response to drug; viral reproduction; late endosome to vacuole transport; cytokinesis; CVT pathway; cellular response to nitrogen starvation; negative regulation of cell proliferation; response to vitamin E; lysosome organization and biogenesis; regulation of catalytic activity; beta-amyloid metabolic process; mitochondrion degradation; response to hypoxia; neuron development; cellular defense response; positive regulation of macroautophagy; defense response to virus; positive regulation of autophagy; autophagic vacuole formation; negative regulation of apoptosis
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 Research Articles on BECLIN 1    1. Beclin 1 is critical for breast cancer stem-like cells maintenance and tumor development
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BECLIN 1 elisa kitPathways associated with BECLIN 1 elisa kit
 Reference Product  PubMed Publications
 BCL2L1 elisa kit  >41 publications with BECLIN 1 and BCL2L1
 UVRAG elisa kit  >30 publications with BECLIN 1 and UVRAG
 BCL2 elisa kit  >24 publications with BECLIN 1 and BCL2
 ATG14 elisa kit  >14 publications with BECLIN 1 and ATG14
 AMBRA1 elisa kit  >13 publications with BECLIN 1 and AMBRA1
 PIK3R4 elisa kit  >5 publications with BECLIN 1 and PIK3R4
 PIK3C3 elisa kit  >5 publications with BECLIN 1 and PIK3C3
 Products by Pathway  Pathway Diagram
 Regulation Of Autophagy Pathway antibodies  Regulation Of Autophagy Pathway Diagram
 Regulation Of Autophagy Pathway antibodies  Regulation Of Autophagy Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
Diseases associated with BECLIN 1 elisa kitOrgans/Tissues associated with BECLIN 1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >295 publications with BECLIN 1 and Neoplasms
 Nervous System Diseases Antibodies  >74 publications with BECLIN 1 and Nervous System Diseases
 Breast Neoplasms Antibodies  >50 publications with BECLIN 1 and Breast Neoplasms
 Necrosis Antibodies  >41 publications with BECLIN 1 and Necrosis
 Liver Diseases Antibodies  >37 publications with BECLIN 1 and Liver Diseases
 Cardiovascular Diseases Antibodies  >32 publications with BECLIN 1 and Cardiovascular Diseases
 Drug Toxicity Antibodies  >31 publications with BECLIN 1 and Drug Toxicity
 Carcinoma, Hepatocellular Antibodies  >31 publications with BECLIN 1 and Carcinoma, Hepatocellular
 Inflammation Antibodies  >24 publications with BECLIN 1 and Inflammation
 Ovarian Neoplasms Antibodies  >20 publications with BECLIN 1 and Ovarian Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >62 publications with BECLIN 1 and Brain
 Liver Antibodies  >48 publications with BECLIN 1 and Liver
 Blood Antibodies  >38 publications with BECLIN 1 and Blood
 Muscle Antibodies  >31 publications with BECLIN 1 and Muscle
 Heart Antibodies  >26 publications with BECLIN 1 and Heart
 Lung Antibodies  >26 publications with BECLIN 1 and Lung
 Vascular Antibodies  >23 publications with BECLIN 1 and Vascular
 Nerve Antibodies  >22 publications with BECLIN 1 and Nerve
 Prostate Antibodies  >20 publications with BECLIN 1 and Prostate
 Lymph Antibodies  >19 publications with BECLIN 1 and Lymph
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