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CSN1 elisa kit :: Camel Casein Alpha ELISA Kit

Scan QR to view Datasheet Catalog #    MBS052258 CSN1 elisa kit
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 Product Name   

Casein Alpha (CSN1), ELISA Kit

 Also Known As   

Camel Casein Alpha ELISA Kit

 Product Gene Name   

CSN1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    115440
 3D Structure    ModBase 3D Structure for P68400
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 Species Reactivity    Camel
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CSN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CSN1 purchase    MBS052258 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Casein Alpha (CSN1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CSN1. The ELISA analytical biochemical technique of the MBS052258 kit is based on CSN1 antibody-CSN1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CSN1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CSN1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CSN1. It may not necessarily be applicable to this product.
 NCBI GI #    29570793
 NCBI GeneID    1457
 NCBI Accession #    NP_808228.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_177560.2 [Other Products]
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 UniProt Primary Accession #    P68400 [Other Products]
 UniProt Secondary Accession #    P19138; P20426; Q14013; Q5U065; B4DYS6; D3DVV8 [Other Products]
 UniProt Related Accession #    P68400; Q8NEV1 [Other Products]
 Molecular Weight    45,144 Da
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 NCBI Official Full Name    casein kinase II subunit alpha isoform b
 NCBI Official Synonym Full Names    casein kinase 2, alpha 1 polypeptide
 NCBI Official Symbol    CSNK2A1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    casein kinase II subunit alpha; CK II alpha 3; protein kinase CK2; CK2 catalytic subunit alpha; casein kinase II alpha 1 subunit; casein kinase II alpha 1 polypeptide pseudogene
 UniProt Protein Name    Casein kinase II subunit alpha
 UniProt Gene Name    CSNK2A1 [Similar Products]
 UniProt Synonym Gene Names    CK2A1; CK II alpha [Similar Products]
 UniProt Entry Name    CSK21_HUMAN
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 NCBI Summary for CSN1    Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq, Jul 2014]
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 UniProt Comments for CSN1    CK2A1: an ubiquitous protein kinase of the CK2 family. Exists as a tetramer composed of two catalytic subunits, alpha and alpha-prime, and two regulatory beta subunits. The beta subunits undergo autophosphorylation. The isoforms are rarely specified in publications. Two splice variant isoforms have been found. Participates in Wnt signaling. Phosphorylates E2 ubiquitin conjugating enzyme UBC3B inducing its interaction with beta-TRCp and enhancing beta-catenin degradation. May control IkB-alpha and p27Kip1 degradation. component of a CK2-SPT16-SSRP1 complex composed of SSRP1, PT16 CK2-A1, CK2-A2 and CK2-B the complex associating following UV irradiation. Interacts with RNPS1. Mouse transgene causes mammary gland hyperplasia and lymphoma, and activation by bovine parasites leads to fatal lymphoproliferation. Expression and activity are elevated in lung tumors and breast tumors. Antisense drives apoptosis of tumor cell lines and xenografts. Involved in DNA break repair by phosphorylation of scaffold protein XRCC1, phosphorylation of BRCA1, and phosphorylation of p53 in response to UV irradiation. Drosophila CK2 (Timekeeper) is involved in circadian regulation. Phosphorylates and binds to a major component of the inclusion bodies seen in Parkinson?s patients. Inhibitors: 4,5,6,7-tetrabromobenzotriazole (TBB).

Protein type: EC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; Other group; CK2 family

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: Sin3 complex; plasma membrane; NuRD complex; PcG protein complex; cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; protein N-terminus binding; Hsp90 protein binding; ATP binding

Biological Process: axon guidance; Wnt receptor signaling pathway; transcription, DNA-dependent; rhythmic process; negative regulation of caspase activity; signal transduction; positive regulation of cell growth; protein amino acid phosphorylation; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of protein catabolic process; mitotic cell cycle; positive regulation of Wnt receptor signaling pathway
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 Research Articles on CSN1    1. miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-alpha, CCNJ, and MEGF9.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CSN1 elisa kitPathways associated with CSN1 elisa kit
 Reference Product  PubMed Publications
 JUN elisa kit  >1 publications with CSN1 and JUN
 CSNK2B elisa kit  >1 publications with CSN1 and CSNK2B
 Products by Pathway  Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Condensation Of Prometaphase Chromosomes Pathway antibodies  Condensation Of Prometaphase Chromosomes Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
Diseases associated with CSN1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with CSN1 and Neoplasms
 Brain Diseases Antibodies  >2 publications with CSN1 and Brain Diseases
 Nervous System Diseases Antibodies  >2 publications with CSN1 and Nervous System Diseases
 Oligospermia Antibodies  >1 publications with CSN1 and Oligospermia
 Anemia Antibodies  >1 publications with CSN1 and Anemia
 Weight Gain Antibodies  >1 publications with CSN1 and Weight Gain
 Anemia, Hemolytic Antibodies  >1 publications with CSN1 and Anemia, Hemolytic
 Fever Antibodies  >1 publications with CSN1 and Fever
 Carcinoma, Squamous Cell Antibodies  >1 publications with CSN1 and Carcinoma, Squamous Cell
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