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GRIN2A elisa kit :: Camel Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS072882 GRIN2A elisa kit
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 Product Name   

Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A), ELISA Kit

 Also Known As   

Camel Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A ELISA Kit

 Product Gene Name   

GRIN2A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    138253
 3D Structure    ModBase 3D Structure for Q12879
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 Species Reactivity    Camel
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GRIN2A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GRIN2A purchase    MBS072882 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRIN2A. The ELISA analytical biochemical technique of the MBS072882 kit is based on GRIN2A antibody-GRIN2A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRIN2A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRIN2A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GRIN2A. It may not necessarily be applicable to this product.
 NCBI GI #    4504125
 NCBI GeneID    2903
 NCBI Accession #    NP_000824.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000833.4 [Other Products]
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 UniProt Primary Accession #    Q12879 [Other Products]
 UniProt Secondary Accession #    O00669; Q17RZ6 [Other Products]
 UniProt Related Accession #    Q12879 [Other Products]
 Molecular Weight    165,283 Da
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 NCBI Official Full Name    glutamate receptor ionotropic, NMDA 2A isoform 1
 NCBI Official Synonym Full Names    glutamate receptor, ionotropic, N-methyl D-aspartate 2A
 NCBI Official Symbol    GRIN2A [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    glutamate receptor ionotropic, NMDA 2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor subunit 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1
 UniProt Protein Name    Glutamate receptor ionotropic, NMDA 2A
 UniProt Synonym Protein Names   
Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A
 Protein Family    Glutamate receptor ionotropic
 UniProt Gene Name    GRIN2A [Similar Products]
 UniProt Synonym Gene Names    NMDAR2A; GluN2A; NMDAR2A; NR2A; hNR2A [Similar Products]
 UniProt Entry Name    NMDE1_HUMAN
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 NCBI Summary for GRIN2A    This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
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 UniProt Comments for GRIN2A    NMDAR2A: a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission.

Protein type: Membrane protein, integral; Channel, ligand-gated; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p13.2

Cellular Component: presynaptic membrane; postsynaptic membrane; synaptic vesicle; cell surface; integral to plasma membrane; endoplasmic reticulum; dendrite; plasma membrane; cell junction; N-methyl-D-aspartate selective glutamate receptor complex

Molecular Function: protein binding; extracellular-glutamate-gated ion channel activity; zinc ion binding; calcium channel activity; N-methyl-D-aspartate selective glutamate receptor activity

Biological Process: startle response; positive regulation of apoptosis; regulation of synaptic plasticity; sensory perception of pain; dopamine metabolic process; synaptic transmission; protein localization; learning and/or memory; transport; response to wounding; visual learning; serotonin metabolic process; response to drug; synaptic transmission, glutamatergic; glutamate signaling pathway; response to amphetamine; sleep; memory; response to ethanol; neurogenesis; directional locomotion; ionotropic glutamate receptor signaling pathway; regulation of sensory perception of pain; regulation of excitatory postsynaptic membrane potential; negative regulation of protein catabolic process

Disease: Epilepsy, Focal, With Speech Disorder And With Or Without Mental Retardation
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 Research Articles on GRIN2A    1. Array comparative genomic hybridization (aCGH) is used to confirm genes for epileptic and other neurodevelopmental disorders, including GRIN2A and proline-rich transmembrane protein (PRRT), both found in rolandic epilepsy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GRIN2A elisa kitDiseases associated with GRIN2A elisa kit
 Reference Product  PubMed Publications
 GRIN1 elisa kit  >17 publications with GRIN2A and GRIN1
 GRIN3A elisa kit  >3 publications with GRIN2A and GRIN3A
 DLG4 elisa kit  >2 publications with GRIN2A and DLG4
 CAMK2A elisa kit  >1 publications with GRIN2A and CAMK2A
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >39 publications with GRIN2A and Mental Disorders
 Nervous System Diseases Antibodies  >20 publications with GRIN2A and Nervous System Diseases
 Brain Diseases Antibodies  >19 publications with GRIN2A and Brain Diseases
 Epilepsy Antibodies  >16 publications with GRIN2A and Epilepsy
 Landau-Kleffner Syndrome Antibodies  >7 publications with GRIN2A and Landau-Kleffner Syndrome
 Melanoma Antibodies  >7 publications with GRIN2A and Melanoma
 Movement Disorders Antibodies  >7 publications with GRIN2A and Movement Disorders
 Epilepsy, Rolandic Antibodies  >6 publications with GRIN2A and Epilepsy, Rolandic
 Mood Disorders Antibodies  >5 publications with GRIN2A and Mood Disorders
 Seizures Antibodies  >4 publications with GRIN2A and Seizures
Organs/Tissues associated with GRIN2A elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >32 publications with GRIN2A and Brain
 Skin Antibodies  >4 publications with GRIN2A and Skin
 Muscle Antibodies  >2 publications with GRIN2A and Muscle
 Blood Antibodies  >2 publications with GRIN2A and Blood
 Eye Antibodies  >1 publications with GRIN2A and Eye
 Liver Antibodies  >1 publications with GRIN2A and Liver
 Embryonic Tissue Antibodies  >1 publications with GRIN2A and Embryonic Tissue
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