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MVK elisa kit :: Camel Mevalonate Kinase (MVK) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9357420 MVK elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mevalonate Kinase (MVK), ELISA Kit

 Also Known As   

Camel Mevalonate Kinase (MVK) ELISA Kit

 Product Gene Name   

MVK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Camel
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MVK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MVK purchase    MBS9357420 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mevalonate Kinase (MVK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MVK. The ELISA analytical biochemical technique of the MBS9357420 kit is based on MVK antibody-MVK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MVK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MVK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MVK. It may not necessarily be applicable to this product.
 NCBI GI #    13592007
 NCBI GeneID    81727
 NCBI Accession #    NP_112325.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031063.1 [Other Products]
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 UniProt Related Accession #    P17256 [Other Products]
 Molecular Weight    41,988 Da
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 NCBI Official Full Name    mevalonate kinase
 NCBI Official Synonym Full Names    mevalonate kinase
 NCBI Official Symbol    Mvk [Similar Products]
 NCBI Official Synonym Symbols   
Lrbp
[Similar Products]
 NCBI Protein Information    mevalonate kinase
 UniProt Protein Name    Mevalonate kinase
 Protein Family    Mevalonate kinase
 UniProt Gene Name    Mvk [Similar Products]
 UniProt Synonym Gene Names    MK [Similar Products]
 UniProt Entry Name    KIME_RAT
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 NCBI Summary for MVK    kinase that catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate; involved in the cholesterol biosynthetic pathway [RGD, Feb 2006]
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 UniProt Comments for MVK    MVK: May be a regulatory site in cholesterol biosynthetic pathway. Defects in MVK are the cause of mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy, and ataxia. Defects in MVK are the cause of hyperimmunoglobulinemia D and periodic fever syndrome (HIDS). HIDS is an autosomal recessive disease characterized by recurrent episodes of unexplained high fever associated with skin rash, diarrhea, adenopathy (swollen, tender lymph nodes), athralgias and/or arthritis. Concentration of IgD, and often IgA, are above normal. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

Protein type: RNA-binding; Translation; Kinase, other; EC 2.7.1.36; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis
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 Research Articles on MVK    1. These data suggest that the association of LRBP with luteinizing hormone receptor mRNA results in the translocation of the messenger ribonucleoprotein complex to the p bodies leading to decapping and degradation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MVK elisa kitDiseases associated with MVK elisa kit
 Products by Pathway  Pathway Diagram
 Activation Of Gene Expression By SREBF (SREBP) Pathway antibodies  Activation Of Gene Expression By SREBF (SREBP) Pathway Diagram
 C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies  C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
 C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies  C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
 Cholesterol Biosynthesis Pathway antibodies  Cholesterol Biosynthesis Pathway Diagram
 Cholesterol Biosynthesis Pathway antibodies  Cholesterol Biosynthesis Pathway Diagram
 Cholesterol Metabolism Pathway antibodies  Cholesterol Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Disease Name  Pubmed Publications
 Fever Antibodies  >71 publications with MVK and Fever
 Mevalonate Kinase Deficiency Antibodies  >61 publications with MVK and Mevalonate Kinase Deficiency
 Necrosis Antibodies  >30 publications with MVK and Necrosis
 Inflammation Antibodies  >22 publications with MVK and Inflammation
 Arthralgia Antibodies  >10 publications with MVK and Arthralgia
 Disease Models, Animal Antibodies  >6 publications with MVK and Disease Models, Animal
 Porokeratosis, disseminated superficial actinic 1 Antibodies  >5 publications with MVK and Porokeratosis, disseminated superficial actinic 1
 Liver Diseases Antibodies  >4 publications with MVK and Liver Diseases
 Hyperplasia Antibodies  >3 publications with MVK and Hyperplasia
 Exanthema Antibodies  >3 publications with MVK and Exanthema
Organs/Tissues associated with MVK elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with MVK and Brain
 Spleen Antibodies  >3 publications with MVK and Spleen
 Heart Antibodies  >3 publications with MVK and Heart
 Artery Antibodies  >2 publications with MVK and Artery
 Nerve Antibodies  >2 publications with MVK and Nerve
 Embryonic Tissue Antibodies  >2 publications with MVK and Embryonic Tissue
 Eye Antibodies  >1 publications with MVK and Eye
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