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MAD2L1 elisa kit :: Camel Mitotic Spindle Assembly Checkpoint Protein MAD2A (MAD2L1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9367297 MAD2L1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mitotic Spindle Assembly Checkpoint Protein MAD2A (MAD2L1), ELISA Kit

 Also Known As   

Camel Mitotic Spindle Assembly Checkpoint Protein MAD2A (MAD2L1) ELISA Kit

 Product Gene Name   

MAD2L1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    601467
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 Species Reactivity    Camel
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MAD2L1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MAD2L1 purchase    MBS9367297 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mitotic Spindle Assembly Checkpoint Protein MAD2A (MAD2L1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MAD2L1. The ELISA analytical biochemical technique of the MBS9367297 kit is based on MAD2L1 antibody-MAD2L1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MAD2L1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MAD2L1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MAD2L1. It may not necessarily be applicable to this product.
 NCBI GI #    4505067
 NCBI GeneID    4085
 NCBI Accession #    NP_002349.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002358.3 [Other Products]
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 UniProt Secondary Accession #    Q53F56; Q548X9; Q6IRW7; Q8IZX3 [Other Products]
 UniProt Related Accession #    Q13257 [Other Products]
 Molecular Weight    10,335 Da
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 NCBI Official Full Name    mitotic spindle assembly checkpoint protein MAD2A
 NCBI Official Synonym Full Names    MAD2 mitotic arrest deficient-like 1 (yeast)
 NCBI Official Symbol    MAD2L1 [Similar Products]
 NCBI Official Synonym Symbols   
MAD2; HSMAD2
[Similar Products]
 NCBI Protein Information    mitotic spindle assembly checkpoint protein MAD2A
 UniProt Protein Name    Mitotic spindle assembly checkpoint protein MAD2A
 UniProt Synonym Protein Names   
Mitotic arrest deficient 2-like protein 1; MAD2-like protein 1
 Protein Family    Mitotic spindle assembly checkpoint protein
 UniProt Gene Name    MAD2L1 [Similar Products]
 UniProt Synonym Gene Names    MAD2; HsMAD2; MAD2-like protein 1 [Similar Products]
 UniProt Entry Name    MD2L1_HUMAN
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 NCBI Summary for MAD2L1    MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MAD2L1    MAD2L1: required for the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. Inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate. Interacts with Cdc20, MAD2L1BP and with ADAM17/TACE

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 4q27

Cellular Component: cytosol; kinetochore; nuclear pore; nucleus; perinuclear region of cytoplasm; spindle pole

Molecular Function: identical protein binding; protein binding; protein homodimerization activity

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell division; mitosis; mitotic cell cycle; mitotic cell cycle checkpoint; mitotic cell cycle spindle assembly checkpoint; negative regulation of apoptosis; negative regulation of mitotic cell cycle; negative regulation of protein catabolic process; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; small GTPase mediated signal transduction
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 Research Articles on MAD2L1    1. Data indicate the structure of the intermediate conformer of the multistate checkpoint protein mitotic arrest deficient 2 (Mad2) protein.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MAD2L1 elisa kitPathways associated with MAD2L1 elisa kit
 Reference Product  PubMed Publications
 CDC20 elisa kit  >111 publications with MAD2L1 and CDC20
 MAD1L1 elisa kit  >59 publications with MAD2L1 and MAD1L1
 BUB1B elisa kit  >29 publications with MAD2L1 and BUB1B
 BUB3 elisa kit  >24 publications with MAD2L1 and BUB3
 MAD2L1BP elisa kit  >20 publications with MAD2L1 and MAD2L1BP
 CDC27 elisa kit  >1 publications with MAD2L1 and CDC27
 CDC16 elisa kit  >1 publications with MAD2L1 and CDC16
 Products by Pathway  Pathway Diagram
 APC-Cdc20 Mediated Degradation Of Nek2A Pathway antibodies  APC-Cdc20 Mediated Degradation Of Nek2A Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies  APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
 Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 Amplification Of Signal From Unattached Kinetochores Via A MAD2 Inhibitory Signal Pathway antibodies  Amplification Of Signal From Unattached Kinetochores Via A MAD2 Inhibitory Signal Pathway Diagram
 Amplification Of Signal From The Kinetochores Pathway antibodies  Amplification Of Signal From The Kinetochores Pathway Diagram
 Cdc20:Phospho-APC/C Mediated Degradation Of Cyclin A Pathway antibodies  Cdc20:Phospho-APC/C Mediated Degradation Of Cyclin A Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
Diseases associated with MAD2L1 elisa kitOrgans/Tissues associated with MAD2L1 elisa kit
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >31 publications with MAD2L1 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >20 publications with MAD2L1 and Cell Transformation, Neoplastic
 Breast Neoplasms Antibodies  >20 publications with MAD2L1 and Breast Neoplasms
 Ovarian Neoplasms Antibodies  >13 publications with MAD2L1 and Ovarian Neoplasms
 Lung Neoplasms Antibodies  >13 publications with MAD2L1 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >12 publications with MAD2L1 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >12 publications with MAD2L1 and Liver Diseases
 Neoplasms, Experimental Antibodies  >11 publications with MAD2L1 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >10 publications with MAD2L1 and Liver Neoplasms
 Carcinoma, Squamous Cell Antibodies  >10 publications with MAD2L1 and Carcinoma, Squamous Cell
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >19 publications with MAD2L1 and Lung
 Bone Antibodies  >14 publications with MAD2L1 and Bone
 Blood Antibodies  >14 publications with MAD2L1 and Blood
 Stomach Antibodies  >13 publications with MAD2L1 and Stomach
 Liver Antibodies  >12 publications with MAD2L1 and Liver
 Bone Marrow Antibodies  >9 publications with MAD2L1 and Bone Marrow
 Prostate Antibodies  >7 publications with MAD2L1 and Prostate
 Skin Antibodies  >7 publications with MAD2L1 and Skin
 Lymph Antibodies  >6 publications with MAD2L1 and Lymph
 Kidney Antibodies  >5 publications with MAD2L1 and Kidney
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