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MADCAM-1 elisa kit :: Camel Mucosal Vascular Addressin Cell Adhesion Molecule 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS066415 MADCAM-1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM-1), ELISA Kit

 Also Known As   

Camel Mucosal Vascular Addressin Cell Adhesion Molecule 1 ELISA Kit

 Product Gene Name   

MADCAM-1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 19; NC_000019.9 (496490..505343). Location: 19p13.3
 OMIM    102670
 3D Structure    ModBase 3D Structure for Q13477
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 Species Reactivity    Camel
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of MADCAM-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MADCAM-1 purchase    MBS066415 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM-1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MADCAM-1. The ELISA analytical biochemical technique of the MBS066415 kit is based on MADCAM-1 antibody-MADCAM-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MADCAM-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MADCAM-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MADCAM-1. It may not necessarily be applicable to this product.
 NCBI GI #    109633022
 NCBI GeneID    8174
 NCBI Accession #    NP_570116.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_130760.2 [Other Products]
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 UniProt Primary Accession #    Q13477 [Other Products]
 UniProt Secondary Accession #    O60222; O75867; A5PKV4; B2RPL9 [Other Products]
 UniProt Related Accession #    Q13477 [Other Products]
 Molecular Weight    40,155 Da
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 NCBI Official Full Name    mucosal addressin cell adhesion molecule 1 isoform a
 NCBI Official Synonym Full Names    mucosal vascular addressin cell adhesion molecule 1
 NCBI Official Symbol    MADCAM1 [Similar Products]
 NCBI Official Synonym Symbols   
MACAM1
[Similar Products]
 NCBI Protein Information    mucosal addressin cell adhesion molecule 1; MAdCAM-1; hMAdCAM-1; mucosal addressin cell adhesion molecule-1
 UniProt Protein Name    Mucosal addressin cell adhesion molecule 1
 UniProt Gene Name    MADCAM1 [Similar Products]
 UniProt Synonym Gene Names    MAdCAM-1; hMAdCAM-1 [Similar Products]
 UniProt Entry Name    MADCA_HUMAN
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 NCBI Summary for MADCAM-1    The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MADCAM-1    MADCAM1: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L- selectin binding. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: membrane; integral to membrane; plasma membrane

Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; regulation of immune response; positive regulation of leukocyte migration; cell-matrix adhesion; signal transduction; receptor clustering; keratinocyte differentiation; heterotypic cell-cell adhesion; immune response; cell adhesion; leukocyte tethering or rolling; aging
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 Research Articles on MADCAM-1    1. Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MADCAM-1 elisa kitPathways associated with MADCAM-1 elisa kit
 Reference Product  PubMed Publications
 ITGA4 elisa kit  >47 publications with MADCAM-1 and ITGA4
 CCL25 elisa kit  >8 publications with MADCAM-1 and CCL25
 CD44 elisa kit  >5 publications with MADCAM-1 and CD44
 LTBR elisa kit  >4 publications with MADCAM-1 and LTBR
 NKX2-3 elisa kit  >3 publications with MADCAM-1 and NKX2-3
 CXCR4 elisa kit  >2 publications with MADCAM-1 and CXCR4
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Paxillin-independent Events Mediated By A4b1 And A4b7 Pathway antibodies  Paxillin-independent Events Mediated By A4b1 And A4b7 Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with MADCAM-1 elisa kitOrgans/Tissues associated with MADCAM-1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >81 publications with MADCAM-1 and Inflammation
 Necrosis Antibodies  >46 publications with MADCAM-1 and Necrosis
 Colitis Antibodies  >45 publications with MADCAM-1 and Colitis
 Inflammatory Bowel Diseases Antibodies  >36 publications with MADCAM-1 and Inflammatory Bowel Diseases
 Vascular Diseases Antibodies  >31 publications with MADCAM-1 and Vascular Diseases
 Lymphoma Antibodies  >28 publications with MADCAM-1 and Lymphoma
 Autoimmune Diseases Antibodies  >25 publications with MADCAM-1 and Autoimmune Diseases
 Liver Diseases Antibodies  >13 publications with MADCAM-1 and Liver Diseases
 Weight Loss Antibodies  >5 publications with MADCAM-1 and Weight Loss
 Pancreatitis Antibodies  >3 publications with MADCAM-1 and Pancreatitis
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >46 publications with MADCAM-1 and Spleen
 Brain Antibodies  >13 publications with MADCAM-1 and Brain
 Heart Antibodies  >5 publications with MADCAM-1 and Heart
 Testis Antibodies  >1 publications with MADCAM-1 and Testis
 Eye Antibodies  >1 publications with MADCAM-1 and Eye
 Thyroid Antibodies  >1 publications with MADCAM-1 and Thyroid
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