NP_001035861.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,066 Da
NCBI Official Full Name
N-acylethanolamine-hydrolyzing acid amidase isoform 2
NCBI Official Synonym Full Names
N-acylethanolamine acid amidase
NCBI Official Synonym Symbols
NCBI Protein Information
N-acylethanolamine-hydrolyzing acid amidase; ASAH-like protein; acid ceramidase-like protein
UniProt Protein Name
N-acylethanolamine-hydrolyzing acid amidase
UniProt Synonym Protein Names
Acid ceramidase-like protein; N-acylsphingosine amidohydrolase-like
UniProt Synonym Gene Names
UniProt Entry Name
NAAA_HUMAN
NCBI Summary for NAAA
This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for NAAA
ASAHL: Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N- palmitoylethanolamine > N-myristoylethanolamine > N- lauroylethanolamine = N-stearoylethanolamine > N- arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N- lauroylsphingosine and N-palmitoylsphingosine. Belongs to the acid ceramidase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; EC 3.5.1.-
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: lysosome; cytoplasm
Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; transcription factor binding
Biological Process: lipid metabolic process
Research Articles on NAAA
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Products associated with NAAA elisa kit
Diseases associated with NAAA elisa kit
Organs/Tissues associated with NAAA elisa kit
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