NP_733841.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
62,017 Da
NCBI Official Full Name
testis-specific chromodomain protein Y 1 isoform a
NCBI Official Synonym Full Names
chromodomain Y-linked 1
NCBI Official Synonym Symbols
NCBI Protein Information
testis-specific chromodomain protein Y 1
UniProt Protein Name
Testis-specific chromodomain protein Y 1
UniProt Synonym Gene Names
NCBI Summary for CDY1
This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for CDY1
CDY1: Has histone acetyltransferase activity, with a preference for histone H4. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Acetyltransferase; EC 2.3.1.48
Chromosomal Location of Human Ortholog: Yq11.23
Cellular Component: nucleus
Molecular Function: histone acetyltransferase activity; methylated histone residue binding
Biological Process: histone acetylation; spermatogenesis
Disease: Spermatogenic Failure, Y-linked, 2
Research Articles on CDY1
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Products associated with CDY1 elisa kit
Diseases associated with CDY1 elisa kit
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