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TGM2 elisa kit :: Camel Transglutaminase 2, Tissue ELISA Kit

Scan QR to view Datasheet Catalog #    MBS061503 TGM2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Transglutaminase 2, Tissue (TGM2), ELISA Kit

 Also Known As   

Camel Transglutaminase 2, Tissue ELISA Kit

 Product Gene Name   

TGM2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    190196
 3D Structure    ModBase 3D Structure for P21980
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 Species Reactivity    Camel
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TGM2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TGM2 purchase    MBS061503 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transglutaminase 2, Tissue (TGM2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TGM2. The ELISA analytical biochemical technique of the MBS061503 kit is based on TGM2 antibody-TGM2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TGM2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TGM2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TGM2. It may not necessarily be applicable to this product.
 NCBI GI #    50593093
 NCBI GeneID    7052
 NCBI Accession #    AAT79353.1 [Other Products]
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 UniProt Primary Accession #    P21980 [Other Products]
 UniProt Secondary Accession #    Q16436; Q6B838; Q9BTN7; Q9UH35; E1P5V9 [Other Products]
 UniProt Related Accession #    P21980 [Other Products]
 Molecular Weight    77,329 Da
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 NCBI Official Full Name    transglutaminase 2
 NCBI Official Synonym Full Names    transglutaminase 2
 NCBI Official Symbol    TGM2 [Similar Products]
 NCBI Official Synonym Symbols   
TG2; TGC; GNAH; HEL-S-45; G-ALPHA-h
[Similar Products]
 NCBI Protein Information    protein-glutamine gamma-glutamyltransferase 2; TG(C); TGase C; TGase H; TGase-2; TGase-H; transglutaminase C; transglutaminase H; transglutaminase-2; tissue transglutaminase; epididymis secretory protein Li 45; protein-glutamine-gamma-glutamyltransferase; C polypeptide, protein-glutamine-gamma-glutamyltransferase
 UniProt Protein Name    Protein-glutamine gamma-glutamyltransferase 2
 UniProt Synonym Protein Names   
Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2
 Protein Family    Protein-glutamine gamma-glutamyltransferase
 UniProt Gene Name    TGM2 [Similar Products]
 UniProt Synonym Gene Names    TG(C); TGC; TGase C; TGase H; TGase-2 [Similar Products]
 UniProt Entry Name    TGM2_HUMAN
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 NCBI Summary for TGM2    Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TGM2    TGM2: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. . Is the autoantigen in coeliac disease and plays a role in apoptosis, cellular differentiation and matrix stabilisation. Three alternatively spliced isoforms have been described.

Protein type: Transferase; EC 2.3.2.13

Chromosomal Location of Human Ortholog: 20q12

Cellular Component: focal adhesion; mitochondrion; plasma membrane; cytosol

Molecular Function: protein domain specific binding; protein binding; GTP binding; protein-glutamine gamma-glutamyltransferase activity; metal ion binding

Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of cell adhesion; positive regulation of apoptosis; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; reduction of endoplasmic reticulum calcium ion concentration; positive regulation of smooth muscle cell proliferation; blood vessel remodeling; apoptotic cell clearance; protein homooligomerization; positive regulation of inflammatory response; elevation of mitochondrial calcium ion concentration
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 Research Articles on TGM2    1. Accumulation of TG2 in tumor stroma is an independent risk factor for identifying breast cancer patients at high risk of recurrence.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TGM2 elisa kitPathways associated with TGM2 elisa kit
 Reference Product  PubMed Publications
 ITGB1 elisa kit  >1 publications with TGM2 and ITGB1
 FN1 elisa kit  >1 publications with TGM2 and FN1
 Products by Pathway  Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Thromboxane A2 Receptor Signaling Pathway antibodies  Thromboxane A2 Receptor Signaling Pathway Diagram
Diseases associated with TGM2 elisa kitOrgans/Tissues associated with TGM2 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >27 publications with TGM2 and Neoplasms
 Inflammation Antibodies  >8 publications with TGM2 and Inflammation
 Lung Neoplasms Antibodies  >6 publications with TGM2 and Lung Neoplasms
 Necrosis Antibodies  >5 publications with TGM2 and Necrosis
 Cardiovascular Diseases Antibodies  >5 publications with TGM2 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >5 publications with TGM2 and Breast Neoplasms
 Fibrosis Antibodies  >4 publications with TGM2 and Fibrosis
 Brain Neoplasms Antibodies  >4 publications with TGM2 and Brain Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with TGM2 and Carcinoma, Hepatocellular
 Ovarian Neoplasms Antibodies  >3 publications with TGM2 and Ovarian Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >10 publications with TGM2 and Lung
 Liver Antibodies  >9 publications with TGM2 and Liver
 Blood Antibodies  >9 publications with TGM2 and Blood
 Brain Antibodies  >9 publications with TGM2 and Brain
 Eye Antibodies  >7 publications with TGM2 and Eye
 Bone Antibodies  >7 publications with TGM2 and Bone
 Skin Antibodies  >7 publications with TGM2 and Skin
 Connective Tissue Antibodies  >5 publications with TGM2 and Connective Tissue
 Vascular Antibodies  >5 publications with TGM2 and Vascular
 Muscle Antibodies  >5 publications with TGM2 and Muscle
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