NP_001295105.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
99809 MW
NCBI Official Full Name
cadherin-2 isoform 2
NCBI Official Synonym Full Names
cadherin 2
NCBI Protein Information
cadherin-2
UniProt Protein Name
Cadherin-2
UniProt Synonym Protein Names
CDw325; Neural cadherin; N-cadherin; CD_antigen: CD325
UniProt Synonym Gene Names
NCBI Summary for CDH2
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]
UniProt Comments for CDH2
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density ().
Research Articles on CDH2
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Products associated with CDH2 elisa kit
Pathways associated with CDH2 elisa kit
Diseases associated with CDH2 elisa kit
Organs/Tissues associated with CDH2 elisa kit
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