NP_061870.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,742 Da
NCBI Official Full Name
28S ribosomal protein S21, mitochondrial
NCBI Official Synonym Full Names
mitochondrial ribosomal protein S21
NCBI Protein Information
28S ribosomal protein S21, mitochondrial; S21mt; mitochondrial 28S ribosomal protein S21
UniProt Protein Name
28S ribosomal protein S21, mitochondrial
UniProt Synonym Gene Names
UniProt Entry Name
RT21_HUMAN
NCBI Summary for MRPS21
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for MRPS21
MRPS21: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]
Protein type: Mitochondrial; Ribosomal
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: mitochondrial inner membrane; mitochondrial small ribosomal subunit
Molecular Function: structural constituent of ribosome
Biological Process: mitochondrial translation; translation; organelle organization and biogenesis
Research Articles on MRPS21
Precautions
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Pathways associated with MRPS21 elisa kit
Organs/Tissues associated with MRPS21 elisa kit
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