Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow ADAM19 rightarrow Canine ADAM19  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Creatine Kinase MB isoenzyme (CKMB) ELISA Kit
 • Cross Linked C-Telopeptide Of Type I Collagen (CTXI) Antibody
 • Testosterone Protein
 • FOLATE BINDING PROTEIN (FOLR1) Antibody
 • Cytokeratin 8 (KRT8) Antibody
 • Neutrophil gelatinase-associated lipocalin (LCN2) Recombinant Protein
 • Interleukin-7 (IL-7) ELISA Kit
 • Boc-Glu-Lys-Lys-MCA Enzyme Substrate
 • CD274 Antibody
 • SPIN1 Antibody
 • solute carrier family 34 (sodium phosphate) , member 3 (SLC3... ELISA Kit
 • inositol-3-phosphate synthase 1 (ISYNA1) ELISA Kit
 • Activin A Receptor Type I (ACVR1) Recombinant Protein
 • HA (A-New Caledonia-20-99)(H1N1) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

ADAM19 elisa kit :: Canine A Disintegrin And Metalloprotease 19 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS753120
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloprotease 19 (ADAM19), ELISA Kit

 Also Known As   

Canine A Disintegrin And Metalloprotease 19 ELISA Kit

 Product Gene Name   

ADAM19 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    603640
Section Bar
 Species Reactivity    Canine
Section Bar
 Specificity    This assay has high sensitivity and excellent specificity for detection of ADAM19. No significant cross-reactivity or interference between ADAM19 and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between ADAM19 and all the analogues, therefore, cross reaction may still exist in some cases.
Section Bar
 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    0.5-10ng/mL
 Sensitivity    0.1ng/mL
 Intended Uses    This ADAM19 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Canine ADAM19. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADAM19 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADAM19 purchase    MBS753120 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the A Disintegrin And Metalloprotease 19 (ADAM19) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5-10ng/mL in biological research samples containing ADAM19, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS753120 kit is based on ADAM19 antibody-ADAM19 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADAM19 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADAM19. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Related Product Information for ADAM19 elisa kit

   Principle of the assay: ADAM19 ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-ADAM19 antibody and an ADAM19-HRP conjugate. The assay sample and buffer are incubated together with ADAM19-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the ADAM19 concentration since ADAM19 from samples and ADAM19-HRP conjugate compete for the anti-ADAM19 antibody binding site. Since the number of sites is limited, as more sites are occupied by ADAM19 from the sample, fewer sites are left to bind ADAM19-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The ADAM19 concentration in each sample is interpolated from this standard curve.
 Product Categories/Family for ADAM19 elisa kit    Cell Biology
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of ADAM19 elisa kit    ADAM19 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS753120. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ADAM19. It may not necessarily be applicable to this product.
 NCBI GI #    38197238
 NCBI GeneID    8728
 NCBI Accession #    AAH24214.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q9BZL5; Q9UHP2 [Other Products]
 UniProt Related Accession #    Q9H013 [Other Products]
 Molecular Weight    100,848 Da
Table BarTOPTable Bar
 NCBI Official Full Name    ADAM19 protein, partial
 NCBI Official Synonym Full Names    ADAM metallopeptidase domain 19
 NCBI Official Symbol    ADAM19 [Similar Products]
 NCBI Official Synonym Symbols   
MLTNB; FKSG34; MADDAM
[Similar Products]
 NCBI Protein Information    disintegrin and metalloproteinase domain-containing protein 19; ADAM 19; meltrin-beta; metalloprotease-disintegrin meltrin beta; metalloprotease and disintegrin dendritic antigen marker; a disintegrin and metalloproteinase domain 19 (meltrin beta)
 UniProt Protein Name    Disintegrin and metalloproteinase domain-containing protein 19
 UniProt Synonym Protein Names   
Meltrin-beta; Metalloprotease and disintegrin dendritic antigen marker; MADDAM
 Protein Family    Disintegrin and metalloproteinase domain-containing protein
 UniProt Gene Name    ADAM19 [Similar Products]
 UniProt Synonym Gene Names    MLTNB; FKSG34; ADAM 19; MADDAM [Similar Products]
 UniProt Entry Name    ADA19_HUMAN
Section Bar
 NCBI Summary for ADAM19    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013]
Section Bar
 UniProt Comments for ADAM19    ADAM19: Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Protease; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 5q33.3

Cellular Component: integral to membrane

Molecular Function: zinc ion binding; metalloendopeptidase activity; SH3 domain binding

Biological Process: heart development; membrane protein ectodomain proteolysis
Table BarTOPTable Bar
 Research Articles on ADAM19    1. ADAM19 was upregulated in patients with ulcerative colitis and, to a lesser extent, in patients with Crohn's disease compared with normal controls. In contrast, ADAM9 and ADAM10 expression did not differ between patients with IBD and controls.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with ADAM19 elisa kitDiseases associated with ADAM19 elisa kit
 Reference Product  PubMed Publications
 FURIN elisa kit  >4 publications with ADAM19 and FURIN
 NRG1 elisa kit  >3 publications with ADAM19 and NRG1
 TNFSF11 elisa kit  >1 publications with ADAM19 and TNFSF11
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >14 publications with ADAM19 and Necrosis
 Cardiovascular Diseases Antibodies  >9 publications with ADAM19 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >5 publications with ADAM19 and Nervous System Diseases
 Inflammation Antibodies  >5 publications with ADAM19 and Inflammation
 Kidney Diseases Antibodies  >4 publications with ADAM19 and Kidney Diseases
 Brain Diseases Antibodies  >4 publications with ADAM19 and Brain Diseases
 Ovarian Neoplasms Antibodies  >3 publications with ADAM19 and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >2 publications with ADAM19 and Disease Models, Animal
 Hypertension Antibodies  >2 publications with ADAM19 and Hypertension
 Atrophy Antibodies  >2 publications with ADAM19 and Atrophy
Organs/Tissues associated with ADAM19 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >17 publications with ADAM19 and Heart
 Lung Antibodies  >11 publications with ADAM19 and Lung
 Bone Antibodies  >11 publications with ADAM19 and Bone
 Embryonic Tissue Antibodies  >11 publications with ADAM19 and Embryonic Tissue
 Brain Antibodies  >9 publications with ADAM19 and Brain
 Blood Antibodies  >9 publications with ADAM19 and Blood
 Kidney Antibodies  >5 publications with ADAM19 and Kidney
 Vascular Antibodies  >5 publications with ADAM19 and Vascular
 Placenta Antibodies  >4 publications with ADAM19 and Placenta
 Lymph Node Antibodies  >3 publications with ADAM19 and Lymph Node
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions