NP_076952.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,776 Da
NCBI Official Full Name
ADP-ribose pyrophosphatase, mitochondrial isoform a
NCBI Official Synonym Full Names
nudix (nucleoside diphosphate linked moiety X)-type motif 9
NCBI Official Synonym Symbols
NCBI Protein Information
ADP-ribose pyrophosphatase, mitochondrial; ADPR-PPase; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrosphosphatase NUDT9; adenosine diphosphoribose pyrophosphatase; nucleoside diphosphate linked moiety X-type motif 9
UniProt Protein Name
ADP-ribose pyrophosphatase, mitochondrial
UniProt Synonym Protein Names
ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase; Nucleoside diphosphate-linked moiety X motif 9; Nudix motif 9
UniProt Synonym Gene Names
UniProt Entry Name
NUDT9_HUMAN
NCBI Summary for NUDT9
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for NUDT9
NUDT9: Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'- phosphate. Belongs to the Nudix hydrolase family. NudF subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.1.13; Nucleotide Metabolism - purine; Mitochondrial; Hydrolase
Chromosomal Location of Human Ortholog: 4q22.1
Cellular Component: mitochondrial matrix; intracellular
Molecular Function: ADP-ribose diphosphatase activity; ADP-sugar diphosphatase activity; adenosine-diphosphatase activity
Biological Process: nucleobase, nucleoside and nucleotide metabolic process; ADP catabolic process; IDP catabolic process
Research Articles on NUDT9
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Products associated with NUDT9 elisa kit
Pathways associated with NUDT9 elisa kit
Diseases associated with NUDT9 elisa kit
Organs/Tissues associated with NUDT9 elisa kit
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