NP_065697.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,797 Da
NCBI Official Full Name
achaete-scute homolog 3
NCBI Official Synonym Full Names
achaete-scute family bHLH transcription factor 3
NCBI Protein Information
achaete-scute homolog 3; ASH-3; achaete-scute complex homolog 3; bHLH transcriptional regulator Sgn-1; class A basic helix-loop-helix protein 42; bHLH transcription factor Sgn-1 (Salivary Glands 1)
UniProt Protein Name
Achaete-scute homolog 3
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 42; bHLHa42; bHLH transcriptional regulator Sgn-1
UniProt Synonym Gene Names
UniProt Entry Name
ASCL3_HUMAN
NCBI Summary for ASCL3
Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
UniProt Comments for ASCL3
ASCL3: Transcriptional repressor. Inhibits myogenesis.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 11p15.3
Cellular Component: transcription factor complex; nucleus
Molecular Function: protein dimerization activity; DNA binding
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
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Diseases associated with ASCL3 elisa kit
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